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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRAMEF8
All Species:
9.09
Human Site:
S72
Identified Species:
28.57
UniProt:
Q5VWM4
Number Species:
7
Phosphosite Substitution
Charge Score:
0.43
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VWM4
NP_001012276.1
474
53669
S72
P
L
G
S
L
M
K
S
P
H
L
E
S
L
K
Chimpanzee
Pan troglodytes
XP_001147495
474
53502
S72
P
L
G
S
L
M
K
S
P
H
L
E
S
L
K
Rhesus Macaque
Macaca mulatta
XP_001118877
699
78170
S297
P
L
G
S
L
M
K
S
R
P
L
E
T
F
G
Dog
Lupus familis
XP_534747
503
56957
E83
P
L
G
A
L
M
K
E
Q
Q
P
H
Q
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC16
493
54950
E67
S
F
Q
Q
L
L
Q
E
C
A
H
C
S
R
A
Rat
Rattus norvegicus
Q569B5
493
54896
E67
S
F
Q
Q
L
L
Q
E
C
A
H
C
S
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q640Z9
509
57042
S67
S
F
H
K
L
L
N
S
N
R
H
C
D
P
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q570C0
594
66780
L84
P
H
F
A
D
F
N
L
V
P
D
G
W
G
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
57.2
53.6
N.A.
27.3
27.5
N.A.
N.A.
N.A.
24.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.8
61.5
69.1
N.A.
45.2
45.4
N.A.
N.A.
N.A.
44.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
66.6
40
N.A.
13.3
13.3
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
46.6
N.A.
26.6
26.6
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
25
0
0
0
0
0
25
0
0
0
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
25
0
0
38
0
0
0
% C
% Asp:
0
0
0
0
13
0
0
0
0
0
13
0
13
0
0
% D
% Glu:
0
0
0
0
0
0
0
38
0
0
0
38
0
13
0
% E
% Phe:
0
38
13
0
0
13
0
0
0
0
0
0
0
13
0
% F
% Gly:
0
0
50
0
0
0
0
0
0
0
0
13
0
13
25
% G
% His:
0
13
13
0
0
0
0
0
0
25
38
13
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
13
0
0
50
0
0
0
0
0
0
0
25
% K
% Leu:
0
50
0
0
88
38
0
13
0
0
38
0
0
25
0
% L
% Met:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
25
0
13
0
0
0
0
0
0
% N
% Pro:
63
0
0
0
0
0
0
0
25
25
13
0
0
13
0
% P
% Gln:
0
0
25
25
0
0
25
0
13
13
0
0
13
0
13
% Q
% Arg:
0
0
0
0
0
0
0
0
13
13
0
0
0
25
0
% R
% Ser:
38
0
0
38
0
0
0
50
0
0
0
0
50
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
13
% T
% Val:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _