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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM46C All Species: 31.52
Human Site: S130 Identified Species: 99.05
UniProt: Q5VWP2 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VWP2 NP_060179.2 391 44944 S130 G V N K L K I S P V T L K E A
Chimpanzee Pan troglodytes XP_524818 644 72129 S383 G V N K L K I S P V T L K E A
Rhesus Macaque Macaca mulatta XP_001104234 549 61451 S288 G V N K L K I S P V T L K E A
Dog Lupus familis XP_540260 391 44771 S130 G V N K L K I S P V T L K E A
Cat Felis silvestris
Mouse Mus musculus Q5SSF7 391 44778 S130 G V N K L K I S P V T L K E A
Rat Rattus norvegicus Q5XIV0 391 44780 S130 G V N K L K I S P V T L K E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZL95 390 44734 S129 G V S K L K I S P V T L K E A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7ZUP1 388 44738 T131 G V N K E K I T P M T L K E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.4 70.8 96.6 N.A. 95.9 96.1 N.A. N.A. 89 N.A. 75.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 60.5 71 98.7 N.A. 97.6 98.4 N.A. N.A. 94.8 N.A. 84.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 N.A. 80 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 N.A. 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 13 0 0 0 0 0 0 0 0 100 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 100 0 100 0 0 0 0 0 0 100 0 0 % K
% Leu: 0 0 0 0 88 0 0 0 0 0 0 100 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % M
% Asn: 0 0 88 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 13 0 0 0 0 88 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 13 0 0 100 0 0 0 0 % T
% Val: 0 100 0 0 0 0 0 0 0 88 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _