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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM46C
All Species:
31.52
Human Site:
S158
Identified Species:
99.05
UniProt:
Q5VWP2
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VWP2
NP_060179.2
391
44944
S158
R
W
S
L
I
S
L
S
N
K
N
G
K
N
V
Chimpanzee
Pan troglodytes
XP_524818
644
72129
S411
R
W
S
L
I
S
L
S
N
K
N
G
K
N
V
Rhesus Macaque
Macaca mulatta
XP_001104234
549
61451
S316
R
W
S
L
I
S
L
S
N
K
N
G
K
N
V
Dog
Lupus familis
XP_540260
391
44771
S158
R
W
S
L
I
S
L
S
N
K
N
G
R
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q5SSF7
391
44778
S158
R
W
S
L
I
S
L
S
N
K
N
G
R
N
V
Rat
Rattus norvegicus
Q5XIV0
391
44780
S158
R
W
S
L
I
S
L
S
N
K
N
G
R
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL95
390
44734
S157
R
W
S
L
I
S
L
S
N
K
H
G
R
N
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZUP1
388
44738
S159
R
W
S
L
I
S
L
S
N
N
N
G
R
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.4
70.8
96.6
N.A.
95.9
96.1
N.A.
N.A.
89
N.A.
75.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
60.5
71
98.7
N.A.
97.6
98.4
N.A.
N.A.
94.8
N.A.
84.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% H
% Ile:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
88
0
0
38
0
0
% K
% Leu:
0
0
0
100
0
0
100
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
100
13
88
0
0
100
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
100
0
0
0
0
0
0
0
0
0
0
0
63
0
0
% R
% Ser:
0
0
100
0
0
100
0
100
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% V
% Trp:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _