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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LYPLAL1 All Species: 22.42
Human Site: S111 Identified Species: 41.11
UniProt: Q5VWZ2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VWZ2 NP_620149.1 237 26316 S111 L I D E E V K S G I K K N R I
Chimpanzee Pan troglodytes XP_514204 246 27226 S120 L I D E E V K S G I K K N R I
Rhesus Macaque Macaca mulatta XP_001103738 237 26611 S111 L I D E E V K S G I K K N R I
Dog Lupus familis XP_545715 236 25969 S112 L I D D E V K S G I K K N R I
Cat Felis silvestris
Mouse Mus musculus Q3UFF7 239 26336 T112 L I D E E V K T G I Q K S R I
Rat Rattus norvegicus P70470 230 24690 G107 I D Q E V K N G I P S N R I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511486 222 25127 K99 E V K S G I K K N R I L I G G
Chicken Gallus gallus XP_419411 233 26164 T109 N E M K N G I T K D R I L I G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001013347 228 25395 E105 L G D I V Q D E L R A G I P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097742 235 26221 L109 E V A S G I P L N R I V V G G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001184781 210 23990 V87 S K V I Q Q E V D Q G I P R N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12354 227 24682 I104 E K T V K Q E I D K G I K P E
Red Bread Mold Neurospora crassa Q9HFJ5 245 26967 S113 L I Q K E I D S G I P A D R I
Conservation
Percent
Protein Identity: 100 95.9 94.5 88.6 N.A. 76.1 31.6 N.A. 64.9 72.1 N.A. 56.9 N.A. 45.1 N.A. N.A. 43.4
Protein Similarity: 100 96.3 97.4 93.6 N.A. 85.7 46.4 N.A. 75.9 84.8 N.A. 75.5 N.A. 59 N.A. N.A. 59.9
P-Site Identity: 100 100 100 93.3 N.A. 80 13.3 N.A. 6.6 0 N.A. 13.3 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 20 20 N.A. 13.3 N.A. 13.3 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.3 30.2
Protein Similarity: N.A. N.A. N.A. N.A. 41.3 47.3
P-Site Identity: N.A. N.A. N.A. N.A. 0 53.3
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 0 0 8 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 47 8 0 0 16 0 16 8 0 0 8 0 0 % D
% Glu: 24 8 0 39 47 0 16 8 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 16 8 0 8 47 0 16 8 0 16 24 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 47 0 16 0 24 8 8 8 47 16 24 16 16 54 % I
% Lys: 0 16 8 16 8 8 47 8 8 8 31 39 8 0 8 % K
% Leu: 54 0 0 0 0 0 0 8 8 0 0 8 8 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 8 0 8 0 16 0 0 8 31 0 8 % N
% Pro: 0 0 0 0 0 0 8 0 0 8 8 0 8 16 0 % P
% Gln: 0 0 16 0 8 24 0 0 0 8 8 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 24 8 0 8 54 0 % R
% Ser: 8 0 0 16 0 0 0 39 0 0 8 0 8 0 0 % S
% Thr: 0 0 8 0 0 0 0 16 0 0 0 0 0 0 0 % T
% Val: 0 16 8 8 16 39 0 8 0 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _