KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYPLAL1
All Species:
14.55
Human Site:
S185
Identified Species:
26.67
UniProt:
Q5VWZ2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VWZ2
NP_620149.1
237
26316
S185
A
D
E
L
V
L
H
S
W
A
E
E
T
N
S
Chimpanzee
Pan troglodytes
XP_514204
246
27226
S194
A
D
E
L
V
L
H
S
W
A
E
E
T
N
S
Rhesus Macaque
Macaca mulatta
XP_001103738
237
26611
S185
A
D
E
L
V
L
H
S
W
A
E
E
T
N
A
Dog
Lupus familis
XP_545715
236
25969
S186
A
D
E
L
V
L
H
S
W
G
E
E
T
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3UFF7
239
26336
A186
A
D
N
L
V
L
H
A
W
G
K
E
T
N
S
Rat
Rattus norvegicus
P70470
230
24690
F181
D
P
L
V
P
L
M
F
G
S
L
T
V
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511486
222
25127
E173
V
P
H
S
W
G
R
E
T
N
S
R
L
R
S
Chicken
Gallus gallus
XP_419411
233
26164
E183
L
V
L
Y
S
W
G
E
E
T
N
K
M
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013347
228
25395
V179
H
G
T
S
D
E
L
V
F
H
D
W
G
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097742
235
26221
L183
L
V
P
K
D
W
G
L
E
T
F
E
N
L
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001184781
210
23990
L161
G
Q
V
D
P
L
V
L
Y
E
W
G
E
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12354
227
24682
I178
D
M
D
P
V
V
P
I
G
L
G
I
K
A
K
Red Bread Mold
Neurospora crassa
Q9HFJ5
245
26967
Y187
D
A
D
P
V
V
N
Y
K
L
G
T
M
T
R
Conservation
Percent
Protein Identity:
100
95.9
94.5
88.6
N.A.
76.1
31.6
N.A.
64.9
72.1
N.A.
56.9
N.A.
45.1
N.A.
N.A.
43.4
Protein Similarity:
100
96.3
97.4
93.6
N.A.
85.7
46.4
N.A.
75.9
84.8
N.A.
75.5
N.A.
59
N.A.
N.A.
59.9
P-Site Identity:
100
100
93.3
93.3
N.A.
73.3
6.6
N.A.
6.6
0
N.A.
0
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
20
N.A.
6.6
6.6
N.A.
13.3
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.3
30.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.3
47.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
8
0
0
0
0
0
8
0
24
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
39
16
8
16
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
31
0
0
8
0
16
16
8
31
47
8
16
0
% E
% Phe:
0
0
0
0
0
0
0
8
8
0
8
0
0
0
0
% F
% Gly:
8
8
0
0
0
8
16
0
16
16
16
8
8
0
0
% G
% His:
8
0
8
0
0
0
39
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
8
0
8
8
8
0
24
% K
% Leu:
16
0
16
39
0
54
8
16
0
16
8
0
8
16
0
% L
% Met:
0
8
0
0
0
0
8
0
0
0
0
0
16
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
0
8
8
0
8
39
0
% N
% Pro:
0
16
8
16
16
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
8
0
8
16
% R
% Ser:
0
0
0
16
8
0
0
31
0
8
8
0
0
0
39
% S
% Thr:
0
0
8
0
0
0
0
0
8
16
0
16
39
16
16
% T
% Val:
8
16
8
8
54
16
8
8
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
8
16
0
0
39
0
8
8
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
8
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _