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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYPLAL1
All Species:
8.48
Human Site:
S65
Identified Species:
15.56
UniProt:
Q5VWZ2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VWZ2
NP_620149.1
237
26316
S65
Y
P
T
A
P
P
R
S
Y
T
P
M
K
G
G
Chimpanzee
Pan troglodytes
XP_514204
246
27226
S74
V
G
P
S
F
A
R
S
Y
T
P
M
K
G
G
Rhesus Macaque
Macaca mulatta
XP_001103738
237
26611
S65
Y
P
T
A
P
P
R
S
Y
T
P
M
K
G
G
Dog
Lupus familis
XP_545715
236
25969
P66
Y
P
T
A
P
P
R
P
Y
T
P
M
K
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3UFF7
239
26336
P66
Y
P
T
A
P
S
R
P
Y
T
P
L
K
G
G
Rat
Rattus norvegicus
P70470
230
24690
V61
P
H
A
P
V
M
P
V
T
L
N
M
S
M
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511486
222
25127
R53
P
L
R
P
Y
T
P
R
M
G
E
L
S
P
V
Chicken
Gallus gallus
XP_419411
233
26164
P63
A
P
A
R
P
Y
T
P
M
N
G
A
T
S
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013347
228
25395
S59
R
V
I
Y
P
T
A
S
L
R
P
Y
T
P
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097742
235
26221
L63
P
K
Q
K
Y
T
P
L
D
G
E
L
S
N
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001184781
210
23990
L41
V
I
F
P
S
A
P
L
R
P
Y
T
P
M
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12354
227
24682
L58
V
F
P
N
A
P
E
L
H
V
T
A
N
G
G
Red Bread Mold
Neurospora crassa
Q9HFJ5
245
26967
W67
S
I
P
I
T
A
N
W
G
M
K
M
P
G
W
Conservation
Percent
Protein Identity:
100
95.9
94.5
88.6
N.A.
76.1
31.6
N.A.
64.9
72.1
N.A.
56.9
N.A.
45.1
N.A.
N.A.
43.4
Protein Similarity:
100
96.3
97.4
93.6
N.A.
85.7
46.4
N.A.
75.9
84.8
N.A.
75.5
N.A.
59
N.A.
N.A.
59.9
P-Site Identity:
100
60
100
93.3
N.A.
80
6.6
N.A.
0
13.3
N.A.
20
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
66.6
100
93.3
N.A.
86.6
6.6
N.A.
6.6
13.3
N.A.
20
N.A.
6.6
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.3
30.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.3
47.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
31
8
24
8
0
0
0
0
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
16
0
0
0
0
% E
% Phe:
0
8
8
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
8
16
8
0
0
54
47
% G
% His:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
16
8
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
8
0
0
0
0
0
0
8
0
39
0
0
% K
% Leu:
0
8
0
0
0
0
0
24
8
8
0
24
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
16
8
0
47
0
16
16
% M
% Asn:
0
0
0
8
0
0
8
0
0
8
8
0
8
8
8
% N
% Pro:
24
39
24
24
47
31
31
24
0
8
47
0
16
16
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
8
8
0
0
39
8
8
8
0
0
0
0
0
% R
% Ser:
8
0
0
8
8
8
0
31
0
0
0
0
24
8
0
% S
% Thr:
0
0
31
0
8
24
8
0
8
39
8
8
16
0
8
% T
% Val:
24
8
0
0
8
0
0
8
0
8
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% W
% Tyr:
31
0
0
8
16
8
0
0
39
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _