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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRAMEF6
All Species:
18.79
Human Site:
S290
Identified Species:
59.05
UniProt:
Q5VXH4
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VXH4
NP_001010889.1
476
54852
S290
G
H
L
D
Q
L
L
S
C
L
K
T
S
L
K
Chimpanzee
Pan troglodytes
XP_001153987
513
59439
S327
G
H
L
D
Q
L
L
S
C
L
K
T
S
L
K
Rhesus Macaque
Macaca mulatta
XP_001118879
517
59245
S331
G
H
L
D
Q
L
L
S
C
L
K
T
P
L
K
Dog
Lupus familis
XP_534747
503
56957
R312
N
R
L
D
Q
V
L
R
C
L
M
T
P
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC16
493
54950
S305
G
R
L
D
Q
L
L
S
T
L
Q
R
P
L
E
Rat
Rattus norvegicus
Q569B5
493
54896
S305
G
R
L
D
Q
L
L
S
T
L
Q
R
P
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q640Z9
509
57042
G321
G
R
L
R
Q
L
L
G
G
L
Q
R
P
L
E
Zebra Danio
Brachydanio rerio
Q1L8H0
526
59513
S302
G
H
L
R
K
L
L
S
P
L
N
T
P
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
78.7
51.4
N.A.
29
29.8
N.A.
N.A.
N.A.
26.7
23.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.6
83.7
66.4
N.A.
47.2
47.4
N.A.
N.A.
N.A.
45.5
41.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
53.3
N.A.
60
60
N.A.
N.A.
N.A.
46.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
66.6
N.A.
73.3
73.3
N.A.
N.A.
N.A.
60
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% C
% Asp:
0
0
0
75
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
63
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
88
0
0
0
0
0
0
13
13
0
0
0
0
0
0
% G
% His:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
13
0
0
0
0
0
38
0
0
0
38
% K
% Leu:
0
0
100
0
0
88
100
0
0
100
0
0
0
100
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
13
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
13
0
0
0
75
0
0
% P
% Gln:
0
0
0
0
88
0
0
0
0
0
38
0
0
0
0
% Q
% Arg:
0
50
0
25
0
0
0
13
0
0
0
38
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
75
0
0
0
0
25
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
25
0
0
63
0
0
0
% T
% Val:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _