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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRAMEF7
All Species:
10.3
Human Site:
S277
Identified Species:
45.33
UniProt:
Q5VXH5
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VXH5
NP_001012277.1
474
53653
S277
N
L
S
M
H
S
V
S
F
L
E
G
H
L
D
Chimpanzee
Pan troglodytes
XP_001147495
474
53502
S277
N
L
F
M
H
S
V
S
F
L
E
G
H
L
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534747
503
56957
S301
E
L
Y
L
D
S
I
S
F
L
E
N
R
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC16
493
54950
S294
R
E
L
S
M
G
S
S
L
L
S
G
R
L
D
Rat
Rattus norvegicus
Q569B5
493
54896
S294
R
E
L
S
I
G
S
S
L
L
S
G
R
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q640Z9
509
57042
R311
E
L
N
L
G
S
S
R
L
S
G
R
L
R
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
N.A.
53.6
N.A.
27.3
27.5
N.A.
N.A.
N.A.
24.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.6
N.A.
68.9
N.A.
45.2
45.4
N.A.
N.A.
N.A.
44.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
N.A.
53.3
N.A.
33.3
33.3
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
N.A.
66.6
N.A.
33.3
33.3
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
84
% D
% Glu:
34
34
0
0
0
0
0
0
0
0
50
0
0
0
0
% E
% Phe:
0
0
17
0
0
0
0
0
50
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
17
34
0
0
0
0
17
67
0
0
0
% G
% His:
0
0
0
0
34
0
0
0
0
0
0
0
34
0
0
% H
% Ile:
0
0
0
0
17
0
17
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
67
34
34
0
0
0
0
50
84
0
0
17
84
0
% L
% Met:
0
0
0
34
17
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
34
0
17
0
0
0
0
0
0
0
0
17
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% Q
% Arg:
34
0
0
0
0
0
0
17
0
0
0
17
50
17
0
% R
% Ser:
0
0
17
34
0
67
50
84
0
17
34
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _