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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIPN All Species: 14.55
Human Site: S281 Identified Species: 29.09
UniProt: Q5VXI9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VXI9 NP_001095939.1 398 45534 S281 S R M D V Y M S H A P T G S S
Chimpanzee Pan troglodytes XP_521546 397 45410 S280 S R M D V Y M S H A P T G S S
Rhesus Macaque Macaca mulatta XP_001082459 397 45502 S280 S R M D V Y M S H A P T G S S
Dog Lupus familis XP_853107 430 48478 A294 S R A N V Y V A H T L A G T S
Cat Felis silvestris
Mouse Mus musculus Q3U4B4 400 45725 A283 S R L D V Y M A H A P T G S S
Rat Rattus norvegicus P04634 395 44570 G279 S R F D V Y L G H N P A G T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506638 397 45066 A278 S R A N V Y V A H A P A G T S
Chicken Gallus gallus XP_421661 373 42666 Q265 C P A G T S V Q N M I H W S Q
Frog Xenopus laevis NP_001089697 404 45661 S288 S R V D V Y S S H C P S G T S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O46108 394 44883 A276 E L L E H I K A T S P A G A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q67ZU1 418 46029 A295 S T I D L F L A N E P Q S T S
Baker's Yeast Sacchar. cerevisiae P34163 548 62961 T343 D N M L N S L T R P Y Q I A N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 96.9 48.8 N.A. 81.5 49.7 N.A. 51.5 51.2 52.9 N.A. N.A. 33.9 N.A. N.A. N.A.
Protein Similarity: 100 98.7 97.4 63.4 N.A. 89 67.3 N.A. 68.5 66.5 69.3 N.A. N.A. 54 N.A. N.A. N.A.
P-Site Identity: 100 100 100 46.6 N.A. 86.6 60 N.A. 60 6.6 66.6 N.A. N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 73.3 N.A. 100 73.3 N.A. 86.6 20 86.6 N.A. N.A. 53.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32.5 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. 51.6 37.5 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 25 0 0 0 0 42 0 42 0 34 0 17 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 9 0 0 59 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % E
% Phe: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 0 0 0 9 0 0 0 0 75 0 0 % G
% His: 0 0 0 0 9 0 0 0 67 0 0 9 0 0 0 % H
% Ile: 0 0 9 0 0 9 0 0 0 0 9 0 9 0 0 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % K
% Leu: 0 9 17 9 9 0 25 0 0 0 9 0 0 0 0 % L
% Met: 0 0 34 0 0 0 34 0 0 9 0 0 0 0 0 % M
% Asn: 0 9 0 17 9 0 0 0 17 9 0 0 0 0 9 % N
% Pro: 0 9 0 0 0 0 0 0 0 9 75 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 17 0 0 9 % Q
% Arg: 0 67 0 0 0 0 0 0 9 0 0 0 0 0 0 % R
% Ser: 75 0 0 0 0 17 9 34 0 9 0 9 9 42 84 % S
% Thr: 0 9 0 0 9 0 0 9 9 9 0 34 0 42 0 % T
% Val: 0 0 9 0 67 0 25 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 67 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _