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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIPN All Species: 17.58
Human Site: Y149 Identified Species: 35.15
UniProt: Q5VXI9 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VXI9 NP_001095939.1 398 45534 Y149 S F D E M A K Y D L P G V I D
Chimpanzee Pan troglodytes XP_521546 397 45410 Y148 S F D E M A K Y D L P G V I D
Rhesus Macaque Macaca mulatta XP_001082459 397 45502 Y148 S F D E M A K Y D L P G V I D
Dog Lupus familis XP_853107 430 48478 F162 S Y D E M A R F D L P A V I N
Cat Felis silvestris
Mouse Mus musculus Q3U4B4 400 45725 Y151 S F N E M A K Y D L P G I I D
Rat Rattus norvegicus P04634 395 44570 Y147 S F D E M A K Y D L P A T I N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506638 397 45066 F146 S Y D E M A R F D L P A V I N
Chicken Gallus gallus XP_421661 373 42666 K135 A S V D F I L K K T G Q E Q V
Frog Xenopus laevis NP_001089697 404 45661 K156 S Y D E M A K K D L P A V I D
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O46108 394 44883 I146 M Y D V P A M I D Y V L A K T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q67ZU1 418 46029 V165 N W T W D E L V S Y D L P A M
Baker's Yeast Sacchar. cerevisiae P34163 548 62961 F177 S I D E F A F F D I P N S I E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 96.9 48.8 N.A. 81.5 49.7 N.A. 51.5 51.2 52.9 N.A. N.A. 33.9 N.A. N.A. N.A.
Protein Similarity: 100 98.7 97.4 63.4 N.A. 89 67.3 N.A. 68.5 66.5 69.3 N.A. N.A. 54 N.A. N.A. N.A.
P-Site Identity: 100 100 100 66.6 N.A. 86.6 80 N.A. 66.6 0 80 N.A. N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 86.6 N.A. 93.3 13.3 86.6 N.A. N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32.5 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. 51.6 37.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 84 0 0 0 0 0 34 9 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 75 9 9 0 0 0 84 0 9 0 0 0 42 % D
% Glu: 0 0 0 75 0 9 0 0 0 0 0 0 9 0 9 % E
% Phe: 0 42 0 0 17 0 9 25 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 9 34 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 9 0 9 0 9 0 0 9 75 0 % I
% Lys: 0 0 0 0 0 0 50 17 9 0 0 0 0 9 0 % K
% Leu: 0 0 0 0 0 0 17 0 0 67 0 17 0 0 0 % L
% Met: 9 0 0 0 67 0 9 0 0 0 0 0 0 0 9 % M
% Asn: 9 0 9 0 0 0 0 0 0 0 0 9 0 0 25 % N
% Pro: 0 0 0 0 9 0 0 0 0 0 75 0 9 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % Q
% Arg: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % R
% Ser: 75 9 0 0 0 0 0 0 9 0 0 0 9 0 0 % S
% Thr: 0 0 9 0 0 0 0 0 0 9 0 0 9 0 9 % T
% Val: 0 0 9 9 0 0 0 9 0 0 9 0 50 0 9 % V
% Trp: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 34 0 0 0 0 0 42 0 17 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _