KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IER5
All Species:
12.12
Human Site:
S49
Identified Species:
33.33
UniProt:
Q5VY09
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VY09
NP_057629.2
327
33704
S49
S
A
R
Q
V
Y
L
S
D
P
C
P
G
L
Y
Chimpanzee
Pan troglodytes
XP_520307
238
26159
S20
I
S
L
R
K
I
H
S
S
R
T
Q
R
G
G
Rhesus Macaque
Macaca mulatta
XP_001110964
223
24189
Dog
Lupus familis
XP_860829
243
25975
R25
I
H
S
S
R
T
Q
R
G
G
I
K
L
H
K
Cat
Felis silvestris
Mouse
Mus musculus
O89113
308
31766
S49
S
A
R
Q
V
Y
L
S
D
P
C
P
G
L
Y
Rat
Rattus norvegicus
Q5PQP0
409
42854
S49
N
A
R
Q
L
Y
L
S
E
R
Y
A
E
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517786
265
27117
Q45
L
V
L
R
S
A
R
Q
V
Y
L
S
D
P
C
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66IT9
293
31857
S49
N
A
R
Q
L
Y
L
S
E
R
Y
A
E
L
Y
Zebra Danio
Brachydanio rerio
Q6NYT3
301
32920
N49
N
A
R
Q
V
Y
M
N
E
K
Y
A
E
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.2
29
28.1
N.A.
74
27.8
N.A.
51.9
N.A.
29
29.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
44
39.4
37.3
N.A.
77.3
36.6
N.A.
58.7
N.A.
38.2
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
0
0
N.A.
100
53.3
N.A.
0
N.A.
53.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
0
0
N.A.
100
73.3
N.A.
6.6
N.A.
73.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
56
0
0
0
12
0
0
0
0
0
34
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
23
0
0
0
12
% C
% Asp:
0
0
0
0
0
0
0
0
23
0
0
0
12
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
34
0
0
0
34
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
12
12
0
0
23
12
12
% G
% His:
0
12
0
0
0
0
12
0
0
0
0
0
0
12
0
% H
% Ile:
23
0
0
0
0
12
0
0
0
0
12
0
0
12
0
% I
% Lys:
0
0
0
0
12
0
0
0
0
12
0
12
0
0
12
% K
% Leu:
12
0
23
0
23
0
45
0
0
0
12
0
12
45
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
34
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
23
0
23
0
12
0
% P
% Gln:
0
0
0
56
0
0
12
12
0
0
0
12
0
0
0
% Q
% Arg:
0
0
56
23
12
0
12
12
0
34
0
0
12
0
0
% R
% Ser:
23
12
12
12
12
0
0
56
12
0
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
12
0
0
0
0
12
0
0
0
0
% T
% Val:
0
12
0
0
34
0
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
56
0
0
0
12
34
0
0
0
56
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _