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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEAR1 All Species: 12.73
Human Site: S951 Identified Species: 25.45
UniProt: Q5VY43 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VY43 NP_001073940.1 1037 110666 S951 M E M K G P P S G S P P R Q P
Chimpanzee Pan troglodytes XP_513899 1040 110799 S954 M E M K G P S S G S P P R Q P
Rhesus Macaque Macaca mulatta XP_001116820 662 70281 G577 E M K G P P S G S P P R Q P P
Dog Lupus familis XP_547524 1039 110938 S953 V E M K G P P S G S P P R Q P
Cat Felis silvestris
Mouse Mus musculus Q8VIK5 1034 110562 S949 V E M K G P P S V S P P R Q S
Rat Rattus norvegicus O88281 1574 165428 N1482 D G C L Q Q C N C H T G V P C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507076 1158 124996 R1069 V E M K S P A R R D Y P Y T E
Chicken Gallus gallus P10039 1808 198841 K1670 I G L E N L H K I S S Q G Q Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q90Y57 1242 135325 D1153 P G K E L H C D D K N T V N A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728660 1031 112996 D945 K H K E G Y K D P D E Y D H L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XWD6 1111 118785 G1013 I H G R S A A G R G N N D Y A
Sea Urchin Strong. purpuratus P10079 1064 112055 L964 K T S T G M M L G D Y M T Y N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.2 62.2 87.3 N.A. 84.1 26.7 N.A. 41.1 20 N.A. 20.9 N.A. 32.6 N.A. 28.9 21.8
Protein Similarity: 100 96.8 62.3 90.7 N.A. 88.6 35.4 N.A. 51.8 28.9 N.A. 32.9 N.A. 45.6 N.A. 40.8 34.2
P-Site Identity: 100 93.3 20 93.3 N.A. 80 0 N.A. 33.3 13.3 N.A. 0 N.A. 6.6 N.A. 0 13.3
P-Site Similarity: 100 93.3 26.6 100 N.A. 86.6 6.6 N.A. 40 33.3 N.A. 6.6 N.A. 13.3 N.A. 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 17 0 0 0 0 0 0 0 17 % A
% Cys: 0 0 9 0 0 0 17 0 9 0 0 0 0 0 9 % C
% Asp: 9 0 0 0 0 0 0 17 9 25 0 0 17 0 0 % D
% Glu: 9 42 0 25 0 0 0 0 0 0 9 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 25 9 9 50 0 0 17 34 9 0 9 9 0 0 % G
% His: 0 17 0 0 0 9 9 0 0 9 0 0 0 9 0 % H
% Ile: 17 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % I
% Lys: 17 0 25 42 0 0 9 9 0 9 0 0 0 0 0 % K
% Leu: 0 0 9 9 9 9 0 9 0 0 0 0 0 0 9 % L
% Met: 17 9 42 0 0 9 9 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 9 0 0 17 9 0 9 9 % N
% Pro: 9 0 0 0 9 50 25 0 9 9 42 42 0 17 34 % P
% Gln: 0 0 0 0 9 9 0 0 0 0 0 9 9 42 0 % Q
% Arg: 0 0 0 9 0 0 0 9 17 0 0 9 34 0 0 % R
% Ser: 0 0 9 0 17 0 17 34 9 42 9 0 0 0 9 % S
% Thr: 0 9 0 9 0 0 0 0 0 0 9 9 9 9 0 % T
% Val: 25 0 0 0 0 0 0 0 9 0 0 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 17 9 9 17 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _