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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEAR1 All Species: 9.09
Human Site: T346 Identified Species: 18.18
UniProt: Q5VY43 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VY43 NP_001073940.1 1037 110666 T346 G F T G D R C T D R L C P D G
Chimpanzee Pan troglodytes XP_513899 1040 110799 T349 G F T G D R C T D R L C P D G
Rhesus Macaque Macaca mulatta XP_001116820 662 70281 P9 N G E C S C L P G W A G L H C
Dog Lupus familis XP_547524 1039 110938 A345 G F T G H R C A E R L C P D G
Cat Felis silvestris
Mouse Mus musculus Q8VIK5 1034 110562 T344 G F T G D R C T E R L C P D G
Rat Rattus norvegicus O88281 1574 165428 D772 P P G K T G E D C G A D C P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507076 1158 124996 E365 G Y T G E H C E T R L C S E G
Chicken Gallus gallus P10039 1808 198841 G498 G Y T G E D C G E L R C P N D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q90Y57 1242 135325 A478 G Y R C V C A A G F A G D R C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728660 1031 112996 A344 G W T G A K C A E R I C E A N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XWD6 1111 118785 D367 G Y K G P K C D E R K C D A E
Sea Urchin Strong. purpuratus P10079 1064 112055 L318 G Y T C S C P L G F S G D N C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.2 62.2 87.3 N.A. 84.1 26.7 N.A. 41.1 20 N.A. 20.9 N.A. 32.6 N.A. 28.9 21.8
Protein Similarity: 100 96.8 62.3 90.7 N.A. 88.6 35.4 N.A. 51.8 28.9 N.A. 32.9 N.A. 45.6 N.A. 40.8 34.2
P-Site Identity: 100 100 0 80 N.A. 93.3 0 N.A. 53.3 40 N.A. 6.6 N.A. 40 N.A. 33.3 13.3
P-Site Similarity: 100 100 0 86.6 N.A. 100 0 N.A. 73.3 66.6 N.A. 13.3 N.A. 66.6 N.A. 53.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 9 25 0 0 25 0 0 17 0 % A
% Cys: 0 0 0 25 0 25 67 0 9 0 0 67 9 0 25 % C
% Asp: 0 0 0 0 25 9 0 17 17 0 0 9 25 34 9 % D
% Glu: 0 0 9 0 17 0 9 9 42 0 0 0 9 9 17 % E
% Phe: 0 34 0 0 0 0 0 0 0 17 0 0 0 0 0 % F
% Gly: 84 9 9 67 0 9 0 9 25 9 0 25 0 0 42 % G
% His: 0 0 0 0 9 9 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % I
% Lys: 0 0 9 9 0 17 0 0 0 0 9 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 9 9 0 9 42 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 0 0 0 17 9 % N
% Pro: 9 9 0 0 9 0 9 9 0 0 0 0 42 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 9 0 0 34 0 0 0 59 9 0 0 9 0 % R
% Ser: 0 0 0 0 17 0 0 0 0 0 9 0 9 0 0 % S
% Thr: 0 0 67 0 9 0 0 25 9 0 0 0 0 0 0 % T
% Val: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 42 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _