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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEAR1
All Species:
18.79
Human Site:
Y355
Identified Species:
37.58
UniProt:
Q5VY43
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VY43
NP_001073940.1
1037
110666
Y355
R
L
C
P
D
G
F
Y
G
L
S
C
Q
A
P
Chimpanzee
Pan troglodytes
XP_513899
1040
110799
Y358
R
L
C
P
D
G
F
Y
G
L
S
C
Q
A
P
Rhesus Macaque
Macaca mulatta
XP_001116820
662
70281
E18
W
A
G
L
H
C
N
E
S
C
P
Q
D
T
H
Dog
Lupus familis
XP_547524
1039
110938
Y354
R
L
C
P
D
G
L
Y
G
L
S
C
Q
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIK5
1034
110562
Y353
R
L
C
P
D
G
R
Y
G
L
S
C
Q
E
P
Rat
Rattus norvegicus
O88281
1574
165428
R781
G
A
D
C
P
E
G
R
W
G
L
G
C
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507076
1158
124996
Y374
R
L
C
S
E
G
I
Y
G
I
K
C
D
K
Q
Chicken
Gallus gallus
P10039
1808
198841
H507
L
R
C
P
N
D
C
H
N
R
G
R
C
V
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q90Y57
1242
135325
R487
F
A
G
D
R
C
E
R
D
V
D
E
C
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728660
1031
112996
Y353
R
I
C
E
A
N
K
Y
G
L
D
C
N
R
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XWD6
1111
118785
Y376
R
K
C
D
A
E
Q
Y
G
A
D
C
S
K
T
Sea Urchin
Strong. purpuratus
P10079
1064
112055
N327
F
S
G
D
N
C
E
N
N
D
D
E
C
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.2
62.2
87.3
N.A.
84.1
26.7
N.A.
41.1
20
N.A.
20.9
N.A.
32.6
N.A.
28.9
21.8
Protein Similarity:
100
96.8
62.3
90.7
N.A.
88.6
35.4
N.A.
51.8
28.9
N.A.
32.9
N.A.
45.6
N.A.
40.8
34.2
P-Site Identity:
100
100
0
86.6
N.A.
86.6
0
N.A.
46.6
13.3
N.A.
6.6
N.A.
40
N.A.
33.3
0
P-Site Similarity:
100
100
0
86.6
N.A.
86.6
0
N.A.
60
26.6
N.A.
13.3
N.A.
46.6
N.A.
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
0
0
17
0
0
0
0
9
0
0
0
25
0
% A
% Cys:
0
0
67
9
0
25
9
0
0
9
0
59
34
0
0
% C
% Asp:
0
0
9
25
34
9
0
0
9
9
34
0
17
0
0
% D
% Glu:
0
0
0
9
9
17
17
9
0
0
0
17
0
17
17
% E
% Phe:
17
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
25
0
0
42
9
0
59
9
9
9
0
0
0
% G
% His:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
9
% H
% Ile:
0
9
0
0
0
0
9
0
0
9
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
9
0
0
0
9
0
0
17
0
% K
% Leu:
9
42
0
9
0
0
9
0
0
42
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
17
9
9
9
17
0
0
0
9
0
0
% N
% Pro:
0
0
0
42
9
0
0
0
0
0
9
0
0
0
34
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
9
34
9
9
% Q
% Arg:
59
9
0
0
9
0
9
17
0
9
0
9
0
9
0
% R
% Ser:
0
9
0
9
0
0
0
0
9
0
34
0
9
9
17
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
17
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% V
% Trp:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _