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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEAR1
All Species:
16.67
Human Site:
Y816
Identified Species:
33.33
UniProt:
Q5VY43
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VY43
NP_001073940.1
1037
110666
Y816
V
P
P
S
Y
S
H
Y
Y
S
N
P
S
Y
H
Chimpanzee
Pan troglodytes
XP_513899
1040
110799
Y819
V
P
P
S
Y
S
H
Y
Y
S
N
P
S
Y
H
Rhesus Macaque
Macaca mulatta
XP_001116820
662
70281
L450
S
N
P
S
Y
H
T
L
S
Q
C
S
P
N
P
Dog
Lupus familis
XP_547524
1039
110938
Y820
V
P
P
S
Y
S
H
Y
Y
S
N
P
S
Y
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIK5
1034
110562
Y815
V
S
P
S
Y
S
H
Y
Y
S
N
P
S
Y
H
Rat
Rattus norvegicus
O88281
1574
165428
D1318
C
R
Q
G
A
A
C
D
P
V
S
G
A
C
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507076
1158
124996
Y938
G
E
N
T
N
S
H
Y
F
T
N
P
S
Y
H
Chicken
Gallus gallus
P10039
1808
198841
R1214
Y
G
I
S
H
G
F
R
T
Q
A
I
S
A
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q90Y57
1242
135325
L986
V
C
R
E
L
R
H
L
Y
V
T
K
N
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728660
1031
112996
V818
F
A
C
I
I
F
A
V
F
I
Y
Y
R
R
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XWD6
1111
118785
A850
F
T
G
E
F
C
H
A
L
C
P
E
S
T
F
Sea Urchin
Strong. purpuratus
P10079
1064
112055
F814
I
C
A
C
V
P
G
F
T
G
S
N
C
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.2
62.2
87.3
N.A.
84.1
26.7
N.A.
41.1
20
N.A.
20.9
N.A.
32.6
N.A.
28.9
21.8
Protein Similarity:
100
96.8
62.3
90.7
N.A.
88.6
35.4
N.A.
51.8
28.9
N.A.
32.9
N.A.
45.6
N.A.
40.8
34.2
P-Site Identity:
100
100
20
100
N.A.
93.3
0
N.A.
53.3
13.3
N.A.
20
N.A.
0
N.A.
13.3
0
P-Site Similarity:
100
100
20
100
N.A.
93.3
20
N.A.
73.3
20
N.A.
26.6
N.A.
6.6
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
9
9
9
9
0
0
9
0
9
9
9
% A
% Cys:
9
17
9
9
0
9
9
0
0
9
9
0
9
9
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
17
0
0
0
0
0
0
0
9
0
9
0
% E
% Phe:
17
0
0
0
9
9
9
9
17
0
0
0
0
0
9
% F
% Gly:
9
9
9
9
0
9
9
0
0
9
0
9
0
0
0
% G
% His:
0
0
0
0
9
9
59
0
0
0
0
0
0
0
42
% H
% Ile:
9
0
9
9
9
0
0
0
0
9
0
9
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
0
0
0
9
0
0
17
9
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
9
0
9
0
0
0
0
0
42
9
9
9
0
% N
% Pro:
0
25
42
0
0
9
0
0
9
0
9
42
9
0
9
% P
% Gln:
0
0
9
0
0
0
0
0
0
17
0
0
0
0
0
% Q
% Arg:
0
9
9
0
0
9
0
9
0
0
0
0
9
9
9
% R
% Ser:
9
9
0
50
0
42
0
0
9
34
17
9
59
0
0
% S
% Thr:
0
9
0
9
0
0
9
0
17
9
9
0
0
9
17
% T
% Val:
42
0
0
0
9
0
0
9
0
17
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
42
0
0
42
42
0
9
9
0
42
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _