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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECM29
All Species:
8.79
Human Site:
S194
Identified Species:
19.33
UniProt:
Q5VYK3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VYK3
NP_001073867
1845
204291
S194
Y
V
L
N
E
S
Q
S
R
Q
N
S
S
S
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDI5
1840
203699
R189
V
L
N
E
S
Q
S
R
Q
N
S
S
S
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512235
2388
261388
T250
Y
V
L
N
E
S
Q
T
R
Q
N
T
P
S
T
Chicken
Gallus gallus
XP_424915
1849
204410
S194
Y
V
L
N
E
S
Q
S
R
Q
N
M
P
S
G
Frog
Xenopus laevis
NP_001091307
1851
204810
Q195
G
F
V
L
N
E
P
Q
S
R
Q
S
T
P
S
Zebra Danio
Brachydanio rerio
NP_001155958
1867
206028
R188
V
L
N
E
P
P
S
R
P
A
P
S
S
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V677
1890
212068
P189
I
T
Q
E
Q
D
V
P
P
G
L
S
P
Y
S
Honey Bee
Apis mellifera
XP_001121034
1671
189517
V134
I
M
P
A
L
G
H
V
N
I
P
V
D
S
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002299974
1847
203347
G195
Q
G
G
G
C
S
P
G
L
S
I
A
Q
S
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850086
1866
205864
G200
Q
G
G
G
S
S
P
G
L
S
V
F
Q
V
N
Baker's Yeast
Sacchar. cerevisiae
P38737
1868
210413
S191
R
F
F
L
L
V
P
S
K
Q
V
Q
V
S
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
95.5
N.A.
N.A.
68.8
85.5
78
73.5
N.A.
32
37.4
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
97.8
N.A.
N.A.
72.9
93
88.3
84.4
N.A.
53.3
57.9
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
73.3
80
6.6
13.3
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
86.6
80
33.3
20
N.A.
20
13.3
N.A.
N.A.
Percent
Protein Identity:
27.4
N.A.
N.A.
25.5
23.6
N.A.
Protein Similarity:
48.8
N.A.
N.A.
47.2
44
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
20
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
10
0
10
0
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
10
% D
% Glu:
0
0
0
28
28
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
19
10
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
19
19
19
0
10
0
19
0
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
19
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
19
28
19
19
0
0
0
19
0
10
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
19
28
10
0
0
0
10
10
28
0
0
0
19
% N
% Pro:
0
0
10
0
10
10
37
10
19
0
19
0
28
19
0
% P
% Gln:
19
0
10
0
10
10
28
10
10
37
10
10
19
0
19
% Q
% Arg:
10
0
0
0
0
0
0
19
28
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
19
46
19
28
10
19
10
46
28
64
28
% S
% Thr:
0
10
0
0
0
0
0
10
0
0
0
10
10
0
10
% T
% Val:
19
28
10
0
0
10
10
10
0
0
19
10
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
28
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _