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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECM29
All Species:
22.73
Human Site:
Y1159
Identified Species:
50
UniProt:
Q5VYK3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VYK3
NP_001073867
1845
204291
Y1159
D
K
S
M
V
D
K
Y
L
K
E
I
L
Q
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDI5
1840
203699
Y1154
D
K
S
M
V
D
K
Y
L
K
E
I
L
Q
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512235
2388
261388
Y1215
D
K
S
A
V
D
K
Y
L
K
E
I
L
Q
D
Chicken
Gallus gallus
XP_424915
1849
204410
Y1161
D
K
S
M
V
D
K
Y
M
K
E
I
L
D
D
Frog
Xenopus laevis
NP_001091307
1851
204810
Y1162
E
K
N
M
V
D
K
Y
L
L
E
I
L
Q
D
Zebra Danio
Brachydanio rerio
NP_001155958
1867
206028
Y1143
D
K
T
I
V
E
K
Y
F
K
E
I
L
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V677
1890
212068
R1159
D
S
K
E
V
T
E
R
Y
Y
W
E
I
L
R
Honey Bee
Apis mellifera
XP_001121034
1671
189517
S1031
Y
E
W
R
V
R
I
S
C
C
N
A
L
A
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002299974
1847
203347
H1164
P
K
R
T
I
D
Q
H
L
D
L
I
V
D
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850086
1866
205864
H1173
P
K
K
A
V
D
E
H
L
N
H
I
F
D
D
Baker's Yeast
Sacchar. cerevisiae
P38737
1868
210413
L1178
E
S
S
L
T
I
S
L
Y
F
N
D
I
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
95.5
N.A.
N.A.
68.8
85.5
78
73.5
N.A.
32
37.4
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
97.8
N.A.
N.A.
72.9
93
88.3
84.4
N.A.
53.3
57.9
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
93.3
86.6
80
73.3
N.A.
13.3
20
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
93.3
93.3
93.3
93.3
N.A.
26.6
26.6
N.A.
N.A.
Percent
Protein Identity:
27.4
N.A.
N.A.
25.5
23.6
N.A.
Protein Similarity:
48.8
N.A.
N.A.
47.2
44
N.A.
P-Site Identity:
33.3
N.A.
N.A.
40
13.3
N.A.
P-Site Similarity:
60
N.A.
N.A.
53.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
0
0
0
0
0
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% C
% Asp:
55
0
0
0
0
64
0
0
0
10
0
10
0
28
91
% D
% Glu:
19
10
0
10
0
10
19
0
0
0
55
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
10
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
19
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
10
10
10
10
0
0
0
0
73
19
0
0
% I
% Lys:
0
73
19
0
0
0
55
0
0
46
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
10
55
10
10
0
64
19
0
% L
% Met:
0
0
0
37
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
10
19
0
0
0
0
% N
% Pro:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
46
0
% Q
% Arg:
0
0
10
10
0
10
0
10
0
0
0
0
0
0
10
% R
% Ser:
0
19
46
0
0
0
10
10
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
10
10
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
82
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
55
19
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _