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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECM29
All Species:
12.42
Human Site:
Y562
Identified Species:
27.33
UniProt:
Q5VYK3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VYK3
NP_001073867
1845
204291
Y562
P
S
F
P
E
M
V
Y
Y
I
Q
E
K
A
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDI5
1840
203699
Y557
P
S
F
P
E
M
V
Y
Y
I
Q
E
K
A
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512235
2388
261388
Q616
P
S
F
P
E
M
V
Q
Y
I
Q
E
K
A
S
Chicken
Gallus gallus
XP_424915
1849
204410
H562
P
S
F
P
E
M
V
H
Y
I
Q
E
K
A
S
Frog
Xenopus laevis
NP_001091307
1851
204810
S563
P
S
F
P
V
M
V
S
Y
I
L
E
K
A
S
Zebra Danio
Brachydanio rerio
NP_001155958
1867
206028
S554
P
S
F
P
E
M
V
S
Y
I
Q
E
K
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V677
1890
212068
N542
S
S
I
D
H
S
K
N
R
I
S
S
E
S
I
Honey Bee
Apis mellifera
XP_001121034
1671
189517
G456
Y
L
L
L
L
A
S
G
D
D
K
H
E
I
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002299974
1847
203347
N571
M
G
R
S
R
R
Q
N
I
D
F
I
Y
P
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850086
1866
205864
K592
N
H
D
H
K
Y
P
K
F
I
E
M
L
E
Y
Baker's Yeast
Sacchar. cerevisiae
P38737
1868
210413
N565
P
F
W
F
R
V
N
N
A
S
I
N
T
S
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
95.5
N.A.
N.A.
68.8
85.5
78
73.5
N.A.
32
37.4
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
97.8
N.A.
N.A.
72.9
93
88.3
84.4
N.A.
53.3
57.9
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
93.3
93.3
80
86.6
N.A.
13.3
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
93.3
100
80
93.3
N.A.
26.6
13.3
N.A.
N.A.
Percent
Protein Identity:
27.4
N.A.
N.A.
25.5
23.6
N.A.
Protein Similarity:
48.8
N.A.
N.A.
47.2
44
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
0
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
10
0
0
0
0
55
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
0
0
0
10
19
0
0
0
0
0
% D
% Glu:
0
0
0
0
46
0
0
0
0
0
10
55
19
10
0
% E
% Phe:
0
10
55
10
0
0
0
0
10
0
10
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
10
0
10
10
0
0
10
0
0
0
10
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
10
73
10
10
0
10
10
% I
% Lys:
0
0
0
0
10
0
10
10
0
0
10
0
55
0
10
% K
% Leu:
0
10
10
10
10
0
0
0
0
0
10
0
10
0
0
% L
% Met:
10
0
0
0
0
55
0
0
0
0
0
10
0
0
0
% M
% Asn:
10
0
0
0
0
0
10
28
0
0
0
10
0
0
0
% N
% Pro:
64
0
0
55
0
0
10
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
10
10
0
0
46
0
0
0
0
% Q
% Arg:
0
0
10
0
19
10
0
0
10
0
0
0
0
0
10
% R
% Ser:
10
64
0
10
0
10
10
19
0
10
10
10
0
19
46
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
10
10
55
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
10
0
19
55
0
0
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _