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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC6
All Species:
14.55
Human Site:
S777
Identified Species:
40
UniProt:
Q5VYS8
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VYS8
NP_078893.2
1495
171229
S777
G
E
H
V
V
C
G
S
T
R
N
N
E
S
E
Chimpanzee
Pan troglodytes
XP_001138296
1494
171151
S777
G
E
R
V
V
C
G
S
T
R
N
N
E
S
E
Rhesus Macaque
Macaca mulatta
XP_001083489
1490
170506
S773
G
E
H
V
V
C
G
S
T
R
N
N
E
S
E
Dog
Lupus familis
XP_533505
1495
170429
S778
G
E
L
A
I
C
G
S
T
Q
K
N
E
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q5BLK4
1491
169084
E774
L
S
S
S
K
H
P
E
L
Q
N
C
G
S
L
Rat
Rattus norvegicus
XP_001060307
1496
170270
S780
P
E
L
Q
N
C
G
S
L
C
G
L
Q
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508655
1555
173081
N703
G
E
N
L
E
K
P
N
A
E
S
G
C
G
A
Chicken
Gallus gallus
XP_001233427
1543
176383
E771
T
M
T
D
R
D
I
E
T
C
S
T
S
D
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690842
1199
136644
D599
D
E
D
D
D
D
V
D
L
D
E
S
G
C
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.3
87.4
N.A.
80.6
80.2
N.A.
42.3
62.7
N.A.
43.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
97.6
93.1
N.A.
88.5
88.5
N.A.
57.6
75.9
N.A.
56.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
53.3
N.A.
13.3
26.6
N.A.
13.3
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
80
N.A.
20
46.6
N.A.
40
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
0
12
0
0
0
0
12
12
% A
% Cys:
0
0
0
0
0
56
0
0
0
23
0
12
12
12
0
% C
% Asp:
12
0
12
23
12
23
0
12
0
12
0
0
0
12
23
% D
% Glu:
0
78
0
0
12
0
0
23
0
12
12
0
45
0
45
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
56
0
0
0
0
0
56
0
0
0
12
12
23
12
0
% G
% His:
0
0
23
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
12
12
0
0
0
0
12
0
0
0
0
% K
% Leu:
12
0
23
12
0
0
0
0
34
0
0
12
0
0
23
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
12
0
0
12
0
0
45
45
0
0
0
% N
% Pro:
12
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
12
0
0
0
0
0
23
0
0
12
0
0
% Q
% Arg:
0
0
12
0
12
0
0
0
0
34
0
0
0
0
0
% R
% Ser:
0
12
12
12
0
0
0
56
0
0
23
12
12
45
0
% S
% Thr:
12
0
12
0
0
0
0
0
56
0
0
12
0
12
0
% T
% Val:
0
0
0
34
34
0
12
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _