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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNLS All Species: 10.3
Human Site: S178 Identified Species: 22.67
UniProt: Q5VYX0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VYX0 NP_001026879.2 342 37847 S178 G D I T T L I S E C Q R Q Q L
Chimpanzee Pan troglodytes XP_507898 342 37882 S178 G D I T N L I S E C Q R Q Q L
Rhesus Macaque Macaca mulatta XP_001097061 181 20132 S28 R Q Q L E A V S Y S S R Y A L
Dog Lupus familis XP_853051 317 34867 S164 R R Q L E S V S Y S S R Y A L
Cat Felis silvestris
Mouse Mus musculus A7RDN6 342 37579 S178 G D I V N L I S E R Q R E Q L
Rat Rattus norvegicus Q5U2W9 315 34933 P162 D L V I L T M P A P Q I L G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515475 160 18091
Chicken Gallus gallus XP_421554 338 37023 N174 G D I V N I I N E R Q K Q Q L
Frog Xenopus laevis NP_001087333 301 33673 R148 R Q Q L K S V R Y S S R Y A L
Zebra Danio Brachydanio rerio NP_001002607 344 38078 G180 G D V G S L M G E N Q R R K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795826 362 39281 D190 T Q Q C L E K D S G L L E D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 51.4 71.9 N.A. 71.6 72.2 N.A. 26.3 57.3 56.4 59.8 N.A. N.A. N.A. N.A. 45
Protein Similarity: 100 99.7 52.6 81.2 N.A. 86.2 82.4 N.A. 38 75.4 71 80.8 N.A. N.A. N.A. N.A. 65.7
P-Site Identity: 100 93.3 20 20 N.A. 73.3 13.3 N.A. 0 60 13.3 46.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 93.3 26.6 26.6 N.A. 80 26.6 N.A. 0 80 20 80 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 10 0 0 0 0 28 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 19 0 0 0 0 0 % C
% Asp: 10 46 0 0 0 0 0 10 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 19 10 0 0 46 0 0 0 19 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 46 0 0 10 0 0 0 10 0 10 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 37 10 0 10 37 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 10 0 10 0 0 0 0 10 0 10 0 % K
% Leu: 0 10 0 28 19 37 0 0 0 0 10 10 10 0 91 % L
% Met: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 28 0 0 10 0 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % P
% Gln: 0 28 37 0 0 0 0 0 0 0 55 0 28 37 0 % Q
% Arg: 28 10 0 0 0 0 0 10 0 19 0 64 10 0 0 % R
% Ser: 0 0 0 0 10 19 0 46 10 28 28 0 0 0 0 % S
% Thr: 10 0 0 19 10 10 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 19 19 0 0 28 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 28 0 0 0 28 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _