KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIPM
All Species:
14.55
Human Site:
S74
Identified Species:
26.67
UniProt:
Q5VYY2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VYY2
NP_001121687.1
423
48233
S74
T
E
D
G
Y
I
L
S
V
N
R
I
P
R
G
Chimpanzee
Pan troglodytes
XP_001138977
398
45156
L70
T
G
S
R
P
V
V
L
L
Q
H
G
L
V
G
Rhesus Macaque
Macaca mulatta
XP_001082849
423
48312
S74
T
E
D
G
Y
I
L
S
V
N
R
I
P
R
G
Dog
Lupus familis
XP_853107
430
48478
S74
T
E
D
G
Y
I
L
S
V
N
R
I
P
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2A6
422
48235
S74
T
E
D
G
Y
I
L
S
V
N
R
I
P
R
G
Rat
Rattus norvegicus
Q64194
397
45167
Q69
I
P
H
G
R
K
N
Q
F
D
K
G
P
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506638
397
45066
P69
I
P
R
G
V
D
S
P
K
A
A
A
S
R
P
Chicken
Gallus gallus
XP_421661
373
42666
D45
R
I
P
Y
G
R
K
D
L
G
R
S
K
G
P
Frog
Xenopus laevis
NP_001089697
404
45661
P74
I
L
S
V
N
R
I
P
H
G
V
K
Y
E
S
Zebra Danio
Brachydanio rerio
NP_998569
396
44722
G68
S
I
N
R
I
P
H
G
V
K
N
K
N
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46108
394
44883
S66
Y
S
P
K
T
G
E
S
S
N
R
P
V
A
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q67ZU1
418
46029
N77
T
Q
D
G
Y
I
L
N
M
Q
R
I
P
E
G
Baker's Yeast
Sacchar. cerevisiae
P34163
548
62961
I89
V
R
T
E
D
N
Y
I
L
T
L
H
R
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.6
98.1
85.8
N.A.
87.2
52.7
N.A.
72.8
55.3
59.3
53.1
N.A.
34.2
N.A.
N.A.
N.A.
Protein Similarity:
100
93.8
99
91.6
N.A.
92.6
70.4
N.A.
85.1
70.6
74.6
69.2
N.A.
54.6
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
100
13.3
N.A.
13.3
6.6
0
6.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
100
33.3
N.A.
13.3
13.3
6.6
20
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.9
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.5
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
8
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
39
0
8
8
0
8
0
8
0
0
0
0
0
% D
% Glu:
0
31
0
8
0
0
8
0
0
0
0
0
0
24
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
0
8
0
54
8
8
0
8
0
16
0
16
0
8
47
% G
% His:
0
0
8
0
0
0
8
0
8
0
8
8
0
0
0
% H
% Ile:
24
16
0
0
8
39
8
8
0
0
0
39
0
8
0
% I
% Lys:
0
0
0
8
0
8
8
0
8
8
8
16
8
8
0
% K
% Leu:
0
8
0
0
0
0
39
8
24
0
8
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
8
8
8
0
39
8
0
8
0
0
% N
% Pro:
0
16
16
0
8
8
0
16
0
0
0
8
47
0
31
% P
% Gln:
0
8
0
0
0
0
0
8
0
16
0
0
0
8
0
% Q
% Arg:
8
8
8
16
8
16
0
0
0
0
54
0
8
31
0
% R
% Ser:
8
8
16
0
0
0
8
39
8
0
0
8
8
0
8
% S
% Thr:
47
0
8
0
8
0
0
0
0
8
0
0
0
0
0
% T
% Val:
8
0
0
8
8
8
8
0
39
0
8
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
39
0
8
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _