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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIPM All Species: 17.58
Human Site: T281 Identified Species: 32.22
UniProt: Q5VYY2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VYY2 NP_001121687.1 423 48233 T281 L L L G G F N T N N M N M S R
Chimpanzee Pan troglodytes XP_001138977 398 45156 S265 N M N M S R A S V Y A A H T L
Rhesus Macaque Macaca mulatta XP_001082849 423 48312 T281 L L L G G F N T N N M N M S R
Dog Lupus familis XP_853107 430 48478 T281 L L M G G F N T N N M N M S R
Cat Felis silvestris
Mouse Mus musculus Q8K2A6 422 48235 T281 L L L G G F N T N N M N M S R
Rat Rattus norvegicus Q64194 397 45167 G264 N I F F L I C G F N E K N L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506638 397 45066 N264 I L L L G G F N L K N L N M S
Chicken Gallus gallus XP_421661 373 42666 G240 N L F F L L C G F N E R N L N
Frog Xenopus laevis NP_001089697 404 45661 L270 C G N I F F I L S G F N E K N
Zebra Danio Brachydanio rerio NP_998569 396 44722 C263 G N V F F L L C G F D E K N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O46108 394 44883 Y261 E I F L I G G Y D T E Q L D Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q67ZU1 418 46029 N282 V S V I T G K N C C L N A S T
Baker's Yeast Sacchar. cerevisiae P34163 548 62961 S293 K I L F N W K S F N I L P R Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.6 98.1 85.8 N.A. 87.2 52.7 N.A. 72.8 55.3 59.3 53.1 N.A. 34.2 N.A. N.A. N.A.
Protein Similarity: 100 93.8 99 91.6 N.A. 92.6 70.4 N.A. 85.1 70.6 74.6 69.2 N.A. 54.6 N.A. N.A. N.A.
P-Site Identity: 100 0 100 93.3 N.A. 100 6.6 N.A. 20 13.3 13.3 0 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 20 100 100 N.A. 100 13.3 N.A. 26.6 13.3 20 13.3 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.9 23.9 N.A.
Protein Similarity: N.A. N.A. N.A. 50.5 41.6 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 0 0 8 8 8 0 0 % A
% Cys: 8 0 0 0 0 0 16 8 8 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 8 0 0 8 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 24 8 8 0 0 % E
% Phe: 0 0 24 31 16 39 8 0 24 8 8 0 0 0 0 % F
% Gly: 8 8 0 31 39 24 8 16 8 8 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 24 0 16 8 8 8 0 0 0 8 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 16 0 0 8 0 8 8 8 0 % K
% Leu: 31 47 39 16 16 16 8 8 8 0 8 16 8 16 16 % L
% Met: 0 8 8 8 0 0 0 0 0 0 31 0 31 8 0 % M
% Asn: 24 8 16 0 8 0 31 16 31 54 8 47 24 8 24 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % Q
% Arg: 0 0 0 0 0 8 0 0 0 0 0 8 0 8 31 % R
% Ser: 0 8 0 0 8 0 0 16 8 0 0 0 0 39 8 % S
% Thr: 0 0 0 0 8 0 0 31 0 8 0 0 0 8 8 % T
% Val: 8 0 16 0 0 0 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _