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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RRAGB All Species: 19.09
Human Site: S157 Identified Species: 35
UniProt: Q5VZM2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VZM2 NP_006055.3 374 43250 S157 I Y V F D V E S R E L E K D M
Chimpanzee Pan troglodytes XP_001148126 380 43910 S163 I Y V F D V E S R E L E K D M
Rhesus Macaque Macaca mulatta XP_001093743 374 43248 S157 I Y V F D V E S R E L E K D M
Dog Lupus familis XP_852073 374 43236 S157 I Y V F D V E S R E L E K D M
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q63487 374 43173 S157 I Y V F D V E S R E L E K D M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420287 313 36535 L151 R E E D L R R L S R P L E C A
Frog Xenopus laevis Q8QHI3 182 20390 L22 D Q E V R I L L L G L D N A G
Zebra Danio Brachydanio rerio NP_956008 315 36782 L151 R E E D L K R L S R P L S C T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40945 180 20598 I20 F G K K Q M R I L M V G L D A
Honey Bee Apis mellifera XP_001119898 306 35679 L146 R E E D L K R L S L P L E C T
Nematode Worm Caenorhab. elegans Q19705 184 20981 G23 E M R I L I L G L D N A G K T
Sea Urchin Strong. purpuratus XP_001203619 272 31801 K112 L Q R S P Y A K I F C L I H K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q00582 310 35829 S148 Q I M M K N L S E T S S E F G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.6 99.4 98.1 N.A. N.A. 97.5 N.A. N.A. 82.3 20.3 80.4 N.A. 20 71.1 20.3 64.7
Protein Similarity: 100 95.2 99.7 99.1 N.A. N.A. 99.1 N.A. N.A. 82.8 31.5 82.3 N.A. 33.1 76.4 33.4 69.7
P-Site Identity: 100 100 100 100 N.A. N.A. 100 N.A. N.A. 0 6.6 0 N.A. 6.6 0 0 0
P-Site Similarity: 100 100 100 100 N.A. N.A. 100 N.A. N.A. 6.6 20 0 N.A. 20 6.6 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 40.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 54.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 0 0 0 8 0 8 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 24 0 % C
% Asp: 8 0 0 24 39 0 0 0 0 8 0 8 0 47 0 % D
% Glu: 8 24 31 0 0 0 39 0 8 39 0 39 24 0 0 % E
% Phe: 8 0 0 39 0 0 0 0 0 8 0 0 0 8 0 % F
% Gly: 0 8 0 0 0 0 0 8 0 8 0 8 8 0 16 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 39 8 0 8 0 16 0 8 8 0 0 0 8 0 0 % I
% Lys: 0 0 8 8 8 16 0 8 0 0 0 0 39 8 8 % K
% Leu: 8 0 0 0 31 0 24 31 24 8 47 31 8 0 0 % L
% Met: 0 8 8 8 0 8 0 0 0 8 0 0 0 0 39 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 8 0 8 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 0 24 0 0 0 0 % P
% Gln: 8 16 0 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 24 0 16 0 8 8 31 0 39 16 0 0 0 0 0 % R
% Ser: 0 0 0 8 0 0 0 47 24 0 8 8 8 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 24 % T
% Val: 0 0 39 8 0 39 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 39 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _