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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RRAGB All Species: 15.15
Human Site: S219 Identified Species: 27.78
UniProt: Q5VZM2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VZM2 NP_006055.3 374 43250 S219 L S R P L E C S C F R T S I W
Chimpanzee Pan troglodytes XP_001148126 380 43910 S225 L S R P L E C S C F R T S I W
Rhesus Macaque Macaca mulatta XP_001093743 374 43248 S219 L S R P L E C S C F R T S I W
Dog Lupus familis XP_852073 374 43236 A219 L S R P L E C A C F R T S I W
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q63487 374 43173 S219 L S R P L E C S C F R T S I W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420287 313 36535 F194 L E M N L R N F A Q I I E A D
Frog Xenopus laevis Q8QHI3 182 20390 N64 Q S Q G F K L N V W D I G G Q
Zebra Danio Brachydanio rerio NP_956008 315 36782 F194 L E C N L R N F A Q I I E A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40945 180 20598 C62 T V E Y K N I C F T V W D V G
Honey Bee Apis mellifera XP_001119898 306 35679 Q188 E L E Q S L K Q F T N I I D A
Nematode Worm Caenorhab. elegans Q19705 184 20981 W65 K D F Q L N L W D V G G Q K S
Sea Urchin Strong. purpuratus XP_001203619 272 31801 S154 D C T C F R T S I W D E T L Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q00582 310 35829 Q190 I P N M S N H Q S N L K K F K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.6 99.4 98.1 N.A. N.A. 97.5 N.A. N.A. 82.3 20.3 80.4 N.A. 20 71.1 20.3 64.7
Protein Similarity: 100 95.2 99.7 99.1 N.A. N.A. 99.1 N.A. N.A. 82.8 31.5 82.3 N.A. 33.1 76.4 33.4 69.7
P-Site Identity: 100 100 100 93.3 N.A. N.A. 100 N.A. N.A. 13.3 6.6 13.3 N.A. 0 0 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. N.A. 100 N.A. N.A. 13.3 33.3 13.3 N.A. 6.6 0 6.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 40.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 54.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 16 0 0 0 0 16 8 % A
% Cys: 0 8 8 8 0 0 39 8 39 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 0 0 0 8 0 16 0 8 8 16 % D
% Glu: 8 16 16 0 0 39 0 0 0 0 0 8 16 0 0 % E
% Phe: 0 0 8 0 16 0 0 16 16 39 0 0 0 8 0 % F
% Gly: 0 0 0 8 0 0 0 0 0 0 8 8 8 8 8 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 8 0 8 0 16 31 8 39 0 % I
% Lys: 8 0 0 0 8 8 8 0 0 0 0 8 8 8 8 % K
% Leu: 54 8 0 0 62 8 16 0 0 0 8 0 0 8 0 % L
% Met: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 16 0 24 16 8 0 8 8 0 0 0 0 % N
% Pro: 0 8 0 39 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 8 16 0 0 0 16 0 16 0 0 8 0 8 % Q
% Arg: 0 0 39 0 0 24 0 0 0 0 39 0 0 0 0 % R
% Ser: 0 47 0 0 16 0 0 39 8 0 0 0 39 0 8 % S
% Thr: 8 0 8 0 0 0 8 0 0 16 0 39 8 0 0 % T
% Val: 0 8 0 0 0 0 0 0 8 8 8 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 16 0 8 0 0 39 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _