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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP27
All Species:
13.33
Human Site:
Y495
Identified Species:
41.9
UniProt:
Q5VZP5
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.43
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VZP5
NP_001073895.1
1158
130176
Y495
E
K
E
A
S
R
R
Y
H
A
K
S
K
R
E
Chimpanzee
Pan troglodytes
XP_513970
1160
130260
Y497
E
K
E
A
S
R
R
Y
H
A
K
S
K
R
E
Rhesus Macaque
Macaca mulatta
XP_001087527
1164
130670
Y499
E
K
E
A
S
R
R
Y
H
A
K
S
K
R
E
Dog
Lupus familis
XP_547482
1165
129899
R502
K
E
A
A
R
R
Y
R
S
R
S
R
R
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q148W8
1138
128557
Y489
E
K
E
A
A
R
K
Y
R
S
K
S
K
R
E
Rat
Rattus norvegicus
XP_573493
1137
128712
K486
I
E
K
E
A
A
R
K
Y
R
S
K
S
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513010
338
37929
Chicken
Gallus gallus
XP_416655
1177
132665
R519
I
E
K
E
A
V
Q
R
Y
R
S
K
N
K
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
95.3
81.9
N.A.
81.6
80.9
N.A.
21.3
58.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
97
87.9
N.A.
88
88.5
N.A.
25.1
74.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
20
N.A.
73.3
6.6
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
40
N.A.
93.3
40
N.A.
0
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
63
38
13
0
0
0
38
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
50
38
50
25
0
0
0
0
0
0
0
0
0
13
63
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
38
0
0
0
0
0
0
% H
% Ile:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
13
50
25
0
0
0
13
13
0
0
50
25
50
25
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
13
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
13
63
50
25
13
38
0
13
13
50
13
% R
% Ser:
0
0
0
0
38
0
0
0
13
13
38
50
13
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
13
50
25
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _