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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM22G All Species: 1.82
Human Site: S488 Identified Species: 8
UniProt: Q5VZR2 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VZR2 NP_001038942.1 741 79011 S488 L V E K R L L S L K E K G C G
Chimpanzee Pan troglodytes XP_001151833 732 78376 S482 Q M D F L A L S Q E L E Q E E
Rhesus Macaque Macaca mulatta XP_001085053 999 107100 P746 L V E K R L L P L K E K Q R A
Dog Lupus familis XP_852970 689 73371 E442 Q A L A E K L E Q E E G L S L
Cat Felis silvestris
Mouse Mus musculus Q3V0C3 733 80570 A486 L L E K P C P A L K K R G V E
Rat Rattus norvegicus XP_001054929 735 80219 A488 L I E K H C L A L K K K G V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.5 61.6 42.6 N.A. 39.5 41 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 92.4 65.5 54.3 N.A. 53.9 54.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 73.3 13.3 N.A. 40 53.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 40 73.3 20 N.A. 66.6 73.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 17 0 17 0 34 0 0 0 0 0 0 17 % A
% Cys: 0 0 0 0 0 34 0 0 0 0 0 0 0 17 0 % C
% Asp: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 67 0 17 0 0 17 0 34 50 17 0 17 50 % E
% Phe: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 17 50 0 17 % G
% His: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 67 0 17 0 0 0 67 34 50 0 0 0 % K
% Leu: 67 17 17 0 17 34 84 0 67 0 17 0 17 0 17 % L
% Met: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 17 0 17 17 0 0 0 0 0 0 0 % P
% Gln: 34 0 0 0 0 0 0 0 34 0 0 0 34 0 0 % Q
% Arg: 0 0 0 0 34 0 0 0 0 0 0 17 0 17 0 % R
% Ser: 0 0 0 0 0 0 0 34 0 0 0 0 0 17 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 34 0 0 0 0 0 0 0 0 0 0 0 34 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _