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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAPDC1A
All Species:
31.82
Human Site:
S141
Identified Species:
50
UniProt:
Q5VZY2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VZY2
NP_001025230.1
271
30395
S141
L
V
S
E
G
R
K
S
F
P
S
I
H
S
S
Chimpanzee
Pan troglodytes
XP_001170623
223
25141
T94
A
H
S
D
L
M
C
T
G
D
K
D
V
V
N
Rhesus Macaque
Macaca mulatta
XP_001092746
343
37863
C200
R
P
D
F
F
Y
R
C
F
P
D
G
L
A
H
Dog
Lupus familis
XP_535038
333
36609
S203
L
V
S
E
G
R
K
S
F
P
S
I
H
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBU9
271
30425
S141
L
V
S
E
G
R
K
S
F
P
S
I
H
S
S
Rat
Rattus norvegicus
O08564
282
31978
S139
A
V
C
N
P
D
W
S
K
I
N
C
S
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514919
461
51675
S147
L
V
S
E
G
R
K
S
F
P
S
I
H
S
S
Chicken
Gallus gallus
XP_426544
322
36285
S192
L
V
S
E
G
R
K
S
F
P
S
I
H
S
S
Frog
Xenopus laevis
Q6GQ62
226
25153
P97
G
L
H
C
T
G
D
P
E
L
V
I
E
G
R
Zebra Danio
Brachydanio rerio
XP_002664129
282
31516
S148
L
V
S
E
G
R
K
S
F
P
S
S
H
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623887
268
30640
N138
P
D
F
K
C
N
G
N
P
V
V
I
K
D
G
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
S192
L
V
L
E
A
R
K
S
F
Y
S
G
H
S
A
Sea Urchin
Strong. purpuratus
XP_787511
258
29394
S128
T
I
N
E
G
R
K
S
F
P
S
G
H
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI60
290
32684
H160
K
D
V
V
K
E
G
H
K
S
F
P
S
G
H
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
R157
C
T
T
K
N
H
E
R
L
L
D
G
F
R
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
48
77.7
N.A.
99.2
25.5
N.A.
48.1
77.3
52.4
71.2
N.A.
N.A.
47.9
24.3
46.1
Protein Similarity:
100
64.9
60
79.8
N.A.
99.2
41.1
N.A.
53.3
80.4
63.4
83.6
N.A.
N.A.
66.7
39.8
64.2
P-Site Identity:
100
6.6
13.3
100
N.A.
100
13.3
N.A.
100
100
6.6
93.3
N.A.
N.A.
6.6
66.6
73.3
P-Site Similarity:
100
26.6
26.6
100
N.A.
100
20
N.A.
100
100
13.3
93.3
N.A.
N.A.
20
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
31.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.4
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
7
0
0
0
0
0
0
0
0
7
7
% A
% Cys:
7
0
7
7
7
0
7
7
0
0
0
7
0
0
0
% C
% Asp:
0
14
7
7
0
7
7
0
0
7
14
7
0
14
0
% D
% Glu:
0
0
0
54
0
7
7
0
7
0
0
0
7
0
0
% E
% Phe:
0
0
7
7
7
0
0
0
60
0
7
0
7
0
0
% F
% Gly:
7
0
0
0
47
7
14
0
7
0
0
27
0
14
14
% G
% His:
0
7
7
0
0
7
0
7
0
0
0
0
54
0
14
% H
% Ile:
0
7
0
0
0
0
0
0
0
7
0
47
0
0
0
% I
% Lys:
7
0
0
14
7
0
54
0
14
0
7
0
7
0
0
% K
% Leu:
47
7
7
0
7
0
0
0
7
14
0
0
7
0
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
7
7
0
7
0
0
7
0
0
0
7
% N
% Pro:
7
7
0
0
7
0
0
7
7
54
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
54
7
7
0
0
0
0
0
7
7
% R
% Ser:
0
0
47
0
0
0
0
60
0
7
54
7
14
54
47
% S
% Thr:
7
7
7
0
7
0
0
7
0
0
0
0
0
0
7
% T
% Val:
0
54
7
7
0
0
0
0
0
7
14
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _