KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAPDC1A
All Species:
13.64
Human Site:
S246
Identified Species:
21.43
UniProt:
Q5VZY2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VZY2
NP_001025230.1
271
30395
S246
V
S
L
R
V
P
A
S
L
K
K
E
E
R
P
Chimpanzee
Pan troglodytes
XP_001170623
223
25141
C199
P
P
L
T
D
A
E
C
H
K
P
F
Q
D
K
Rhesus Macaque
Macaca mulatta
XP_001092746
343
37863
C305
G
I
T
F
A
Y
V
C
Y
R
Q
Y
Y
P
P
Dog
Lupus familis
XP_535038
333
36609
S308
V
S
L
R
V
P
T
S
L
K
K
D
E
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBU9
271
30425
S246
V
S
L
R
V
P
T
S
L
K
K
E
E
R
P
Rat
Rattus norvegicus
O08564
282
31978
L244
V
V
A
I
L
V
V
L
Y
V
T
D
F
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514919
461
51675
R252
G
Q
Q
M
S
W
G
R
Q
L
A
R
F
Y
A
Chicken
Gallus gallus
XP_426544
322
36285
S297
V
S
L
L
D
Q
N
S
M
K
K
E
E
R
P
Frog
Xenopus laevis
Q6GQ62
226
25153
P202
V
E
R
D
C
H
Q
P
Y
R
N
K
G
R
M
Zebra Danio
Brachydanio rerio
XP_002664129
282
31516
V253
A
S
L
A
A
A
T
V
H
N
M
P
A
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623887
268
30640
P243
D
S
Q
V
C
H
K
P
Y
A
A
L
N
Q
I
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
T297
L
L
P
R
P
P
R
T
P
R
N
S
E
D
E
Sea Urchin
Strong. purpuratus
XP_787511
258
29394
D233
A
R
L
Y
A
L
R
D
A
M
S
L
Q
E
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI60
290
32684
D265
A
Y
F
Q
M
L
A
D
S
R
N
D
V
Q
D
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
D262
P
F
K
P
L
M
D
D
S
D
V
T
L
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
48
77.7
N.A.
99.2
25.5
N.A.
48.1
77.3
52.4
71.2
N.A.
N.A.
47.9
24.3
46.1
Protein Similarity:
100
64.9
60
79.8
N.A.
99.2
41.1
N.A.
53.3
80.4
63.4
83.6
N.A.
N.A.
66.7
39.8
64.2
P-Site Identity:
100
13.3
6.6
86.6
N.A.
93.3
6.6
N.A.
0
66.6
13.3
13.3
N.A.
N.A.
6.6
20
6.6
P-Site Similarity:
100
20
20
93.3
N.A.
93.3
20
N.A.
0
73.3
26.6
13.3
N.A.
N.A.
13.3
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
31.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.4
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
7
7
20
14
14
0
7
7
14
0
7
0
7
% A
% Cys:
0
0
0
0
14
0
0
14
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
14
0
7
20
0
7
0
20
0
14
7
% D
% Glu:
0
7
0
0
0
0
7
0
0
0
0
20
34
14
14
% E
% Phe:
0
7
7
7
0
0
0
0
0
0
0
7
14
7
0
% F
% Gly:
14
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
14
0
0
14
0
0
0
0
0
0
% H
% Ile:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
0
7
0
0
0
7
0
0
34
27
7
0
0
14
% K
% Leu:
7
7
47
7
14
14
0
7
20
7
0
14
7
0
0
% L
% Met:
0
0
0
7
7
7
0
0
7
7
7
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
7
0
0
7
20
0
7
0
0
% N
% Pro:
14
7
7
7
7
27
0
14
7
0
7
7
0
7
34
% P
% Gln:
0
7
14
7
0
7
7
0
7
0
7
0
14
14
7
% Q
% Arg:
0
7
7
27
0
0
14
7
0
27
0
7
0
34
0
% R
% Ser:
0
40
0
0
7
0
0
27
14
0
7
7
0
7
0
% S
% Thr:
0
0
7
7
0
0
20
7
0
0
7
7
0
0
0
% T
% Val:
40
7
0
7
20
7
14
7
0
7
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
7
0
7
0
0
27
0
0
7
7
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _