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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAPDC1A
All Species:
24.55
Human Site:
T169
Identified Species:
38.57
UniProt:
Q5VZY2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VZY2
NP_001025230.1
271
30395
T169
A
G
K
L
H
C
F
T
E
S
G
R
G
K
S
Chimpanzee
Pan troglodytes
XP_001170623
223
25141
A122
A
F
A
G
L
A
F
A
S
F
Y
L
A
G
K
Rhesus Macaque
Macaca mulatta
XP_001092746
343
37863
S228
E
G
R
K
S
F
P
S
G
H
S
S
F
A
F
Dog
Lupus familis
XP_535038
333
36609
T231
A
G
K
L
H
C
F
T
E
S
G
R
G
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBU9
271
30425
T169
A
G
K
L
H
C
F
T
E
S
G
R
G
K
S
Rat
Rattus norvegicus
O08564
282
31978
F167
V
R
E
G
R
L
S
F
Y
S
G
H
S
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514919
461
51675
T175
A
G
K
L
H
C
F
T
E
N
G
R
G
R
S
Chicken
Gallus gallus
XP_426544
322
36285
T220
A
G
K
L
H
C
F
T
E
N
G
R
G
K
S
Frog
Xenopus laevis
Q6GQ62
226
25153
Y125
G
L
G
F
T
A
L
Y
L
A
G
K
L
R
C
Zebra Danio
Brachydanio rerio
XP_002664129
282
31516
T176
A
G
K
L
Q
C
F
T
D
A
G
R
G
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623887
268
30640
L166
T
S
F
G
F
I
A
L
Y
I
A
G
K
L
H
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
L220
Q
A
R
L
G
P
V
L
N
N
R
I
V
V
P
Sea Urchin
Strong. purpuratus
XP_787511
258
29394
E156
A
G
K
L
H
T
F
E
S
R
G
R
G
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI60
290
32684
V188
Y
L
S
G
K
I
R
V
F
D
Q
R
G
H
V
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
C185
G
Y
L
Y
F
W
L
C
G
Q
L
L
T
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
48
77.7
N.A.
99.2
25.5
N.A.
48.1
77.3
52.4
71.2
N.A.
N.A.
47.9
24.3
46.1
Protein Similarity:
100
64.9
60
79.8
N.A.
99.2
41.1
N.A.
53.3
80.4
63.4
83.6
N.A.
N.A.
66.7
39.8
64.2
P-Site Identity:
100
13.3
6.6
100
N.A.
100
13.3
N.A.
86.6
93.3
6.6
73.3
N.A.
N.A.
0
6.6
60
P-Site Similarity:
100
13.3
20
100
N.A.
100
20
N.A.
100
100
26.6
93.3
N.A.
N.A.
0
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
31.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.4
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
7
7
0
0
14
7
7
0
14
7
0
7
7
0
% A
% Cys:
0
0
0
0
0
40
0
7
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% D
% Glu:
7
0
7
0
0
0
0
7
34
0
0
0
0
7
0
% E
% Phe:
0
7
7
7
14
7
54
7
7
7
0
0
7
0
14
% F
% Gly:
14
54
7
27
7
0
0
0
14
0
60
7
54
7
7
% G
% His:
0
0
0
0
40
0
0
0
0
7
0
7
0
7
7
% H
% Ile:
0
0
0
0
0
14
0
0
0
7
0
7
0
0
0
% I
% Lys:
0
0
47
7
7
0
0
0
0
0
0
7
7
27
7
% K
% Leu:
0
14
7
54
7
7
14
14
7
0
7
14
7
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
20
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
7
% P
% Gln:
7
0
0
0
7
0
0
0
0
7
7
0
0
0
0
% Q
% Arg:
0
7
14
0
7
0
7
0
0
7
7
54
0
20
0
% R
% Ser:
0
7
7
0
7
0
7
7
14
27
7
7
7
7
47
% S
% Thr:
7
0
0
0
7
7
0
40
0
0
0
0
7
0
0
% T
% Val:
7
0
0
0
0
0
7
7
0
0
0
0
7
14
7
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
7
0
0
0
7
14
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _