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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BSPRY
All Species:
14.55
Human Site:
S259
Identified Species:
40
UniProt:
Q5W0U4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5W0U4
NP_060158.2
402
44381
S259
L
T
F
S
T
K
K
S
K
A
C
A
D
G
P
Chimpanzee
Pan troglodytes
Q7YR33
465
52211
K322
S
V
R
Y
T
R
Q
K
K
N
L
P
D
S
P
Rhesus Macaque
Macaca mulatta
XP_001101669
404
44864
S261
L
T
F
S
T
K
K
S
K
T
C
A
D
G
P
Dog
Lupus familis
XP_538804
348
39153
L222
F
D
H
W
P
N
A
L
A
A
T
S
F
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80YW5
473
52732
S307
L
T
F
I
A
K
K
S
K
V
C
S
D
E
P
Rat
Rattus norvegicus
Q6P6S3
448
49686
S305
L
T
F
N
A
K
K
S
K
V
C
S
D
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507093
521
57335
T378
L
T
F
N
P
K
K
T
K
V
Y
P
D
G
P
Chicken
Gallus gallus
XP_415546
466
49893
A323
L
T
F
S
P
K
K
A
K
L
D
L
D
G
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687804
463
51315
K317
R
T
I
T
F
Q
P
K
R
Q
R
Q
L
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.5
96.5
75.6
N.A.
69.3
70.5
N.A.
52.7
50.4
N.A.
36.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
39.3
97.2
79.8
N.A.
75.4
76.7
N.A.
63.3
63.5
N.A.
53.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
93.3
6.6
N.A.
66.6
66.6
N.A.
60
66.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
93.3
13.3
N.A.
73.3
80
N.A.
73.3
73.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
23
0
12
12
12
23
0
23
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
45
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
0
0
0
0
12
0
78
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% E
% Phe:
12
0
67
0
12
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
45
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
12
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
67
67
23
78
0
0
0
0
0
0
% K
% Leu:
67
0
0
0
0
0
0
12
0
12
12
12
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
23
0
12
0
0
0
12
0
0
0
0
0
% N
% Pro:
0
0
0
0
34
0
12
0
0
0
0
23
0
12
89
% P
% Gln:
0
0
0
0
0
12
12
0
0
12
0
12
0
12
0
% Q
% Arg:
12
0
12
0
0
12
0
0
12
0
12
0
0
0
0
% R
% Ser:
12
0
0
34
0
0
0
45
0
0
0
34
0
12
0
% S
% Thr:
0
78
0
12
34
0
0
12
0
12
12
0
0
0
0
% T
% Val:
0
12
0
0
0
0
0
0
0
34
0
0
0
0
0
% V
% Trp:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _