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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC23
All Species:
7.58
Human Site:
S127
Identified Species:
27.78
UniProt:
Q5W5X9
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5W5X9
NP_001035745.1
447
50009
S127
N
S
I
V
P
P
Y
S
E
N
T
D
V
F
K
Chimpanzee
Pan troglodytes
XP_001137822
447
49909
S127
N
S
I
V
P
P
Y
S
E
N
T
D
V
F
K
Rhesus Macaque
Macaca mulatta
XP_001101066
447
49930
N127
N
S
I
V
P
P
Y
N
E
N
T
D
V
F
K
Dog
Lupus familis
XP_545827
512
57216
K129
A
V
S
V
T
P
R
K
K
I
Q
N
K
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHY7
488
54590
H127
N
S
I
E
S
P
C
H
N
K
T
D
I
F
K
Rat
Rattus norvegicus
Q4V7F0
446
50253
Y127
N
S
M
E
S
P
Y
Y
N
K
T
D
I
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508409
386
43077
W84
I
C
Y
G
D
C
H
W
K
Q
A
E
A
H
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
94.6
67.1
N.A.
68.4
72.2
N.A.
50.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
96.1
74.6
N.A.
77.2
83.8
N.A.
63.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
13.3
N.A.
53.3
53.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
60
66.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
0
0
0
0
0
15
0
15
0
0
% A
% Cys:
0
15
0
0
0
15
15
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
15
0
0
0
0
0
0
72
0
0
0
% D
% Glu:
0
0
0
29
0
0
0
0
43
0
0
15
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
72
0
% F
% Gly:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
15
15
0
0
0
0
0
15
0
% H
% Ile:
15
0
58
0
0
0
0
0
0
15
0
0
29
0
0
% I
% Lys:
0
0
0
0
0
0
0
15
29
29
0
0
15
0
72
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% L
% Met:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
72
0
0
0
0
0
0
15
29
43
0
15
0
0
0
% N
% Pro:
0
0
0
0
43
86
0
0
0
0
0
0
0
0
15
% P
% Gln:
0
0
0
0
0
0
0
0
0
15
15
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% R
% Ser:
0
72
15
0
29
0
0
29
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
15
0
0
0
0
0
72
0
0
0
0
% T
% Val:
0
15
0
58
0
0
0
0
0
0
0
0
43
0
15
% V
% Trp:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
0
0
0
58
15
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _