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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYSMD4
All Species:
17.27
Human Site:
S251
Identified Species:
38
UniProt:
Q5XG99
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5XG99
NP_689662
296
32066
S251
A
S
G
E
T
P
N
S
L
N
T
T
V
I
P
Chimpanzee
Pan troglodytes
XP_001140819
296
32148
S251
A
S
G
E
T
R
N
S
L
N
T
T
V
I
P
Rhesus Macaque
Macaca mulatta
XP_001103620
296
32466
S251
A
S
G
E
T
P
N
S
L
N
T
T
V
I
P
Dog
Lupus familis
XP_545826
298
32691
S253
S
T
G
E
I
P
S
S
W
N
T
T
T
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CC84
293
31641
G248
A
T
G
E
P
S
N
G
L
N
A
T
V
V
P
Rat
Rattus norvegicus
Q5M836
300
33683
H250
A
K
V
D
V
S
H
H
S
T
V
D
S
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508116
469
51079
S421
R
T
G
G
P
T
S
S
L
N
L
T
A
V
P
Chicken
Gallus gallus
Q5ZKK0
300
33397
H246
V
K
A
D
V
S
H
H
S
T
M
E
S
A
H
Frog
Xenopus laevis
Q6DCC7
289
32035
S242
G
D
S
E
G
T
F
S
I
E
G
R
T
N
V
Zebra Danio
Brachydanio rerio
Q6P606
267
30212
I224
I
A
M
L
L
I
G
I
V
L
P
I
F
Y
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001122475
209
23442
T166
F
V
T
A
R
A
P
T
S
S
S
I
S
V
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
91.5
77.8
N.A.
71.6
32.3
N.A.
36.4
30.3
40.5
36.8
N.A.
N.A.
N.A.
21.2
N.A.
Protein Similarity:
100
97.9
94.9
86.2
N.A.
80.7
50
N.A.
45.8
49.6
57.7
55
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
100
93.3
100
53.3
N.A.
60
6.6
N.A.
40
0
13.3
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
93.3
100
80
N.A.
73.3
20
N.A.
60
13.3
20
13.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
10
10
10
0
10
0
0
0
0
10
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
19
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
55
0
0
0
0
0
10
0
10
0
0
0
% E
% Phe:
10
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% F
% Gly:
10
0
55
10
10
0
10
10
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
19
19
0
0
0
0
0
0
19
% H
% Ile:
10
0
0
0
10
10
0
10
10
0
0
19
0
28
0
% I
% Lys:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
10
0
0
0
46
10
10
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
37
0
0
55
0
0
0
10
0
% N
% Pro:
0
0
0
0
19
28
10
0
0
0
10
0
0
0
55
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
10
10
0
0
0
0
0
10
0
0
0
% R
% Ser:
10
28
10
0
0
28
19
55
28
10
10
0
28
10
0
% S
% Thr:
0
28
10
0
28
19
0
10
0
19
37
55
19
0
0
% T
% Val:
10
10
10
0
19
0
0
0
10
0
10
0
37
37
19
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _