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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BTBD8
All Species:
13.64
Human Site:
Y246
Identified Species:
50
UniProt:
Q5XKL5
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5XKL5
NP_899065.2
378
42793
Y246
W
A
E
S
S
Q
E
Y
V
T
L
Q
G
I
S
Chimpanzee
Pan troglodytes
XP_524768
1792
198781
Y246
W
A
E
S
S
Q
E
Y
V
T
L
Q
G
I
S
Rhesus Macaque
Macaca mulatta
XP_001098569
378
42730
Y246
W
A
E
S
S
Q
E
Y
V
T
L
Q
G
I
S
Dog
Lupus familis
XP_855197
555
60945
Y423
W
A
E
S
S
Q
E
Y
I
T
L
Q
G
I
N
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q5XIU1
478
54046
F330
H
D
I
S
P
D
I
F
T
H
V
L
Y
Y
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512533
143
16433
V15
C
T
S
Y
Q
R
W
V
L
C
K
E
R
I
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GR09
392
44625
R240
M
Q
E
S
R
K
N
R
V
Y
I
R
D
V
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.8
97.3
59.6
N.A.
N.A.
20
N.A.
30.1
N.A.
20.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
21
99.4
63.4
N.A.
N.A.
35.3
N.A.
33.8
N.A.
39
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
N.A.
6.6
N.A.
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
N.A.
20
N.A.
26.6
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
58
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
15
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% C
% Asp:
0
15
0
0
0
15
0
0
0
0
0
0
15
0
15
% D
% Glu:
0
0
72
0
0
0
58
0
0
0
0
15
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
58
0
0
% G
% His:
15
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% H
% Ile:
0
0
15
0
0
0
15
0
15
0
15
0
0
72
0
% I
% Lys:
0
0
0
0
0
15
0
0
0
0
15
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
15
0
58
15
0
0
0
% L
% Met:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
15
% N
% Pro:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
15
0
0
15
58
0
0
0
0
0
58
0
0
0
% Q
% Arg:
0
0
0
0
15
15
0
15
0
0
0
15
15
0
15
% R
% Ser:
0
0
15
86
58
0
0
0
0
0
0
0
0
0
43
% S
% Thr:
0
15
0
0
0
0
0
0
15
58
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
15
58
0
15
0
0
15
15
% V
% Trp:
58
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
15
0
0
0
58
0
15
0
0
15
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _