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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OTP All Species: 15.76
Human Site: S285 Identified Species: 43.33
UniProt: Q5XKR4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5XKR4 NP_115485.1 325 34159 S285 P A S L P G P S N V S G S P Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546055 392 40744 S352 P A S L P G P S N V S G S P Q
Cat Felis silvestris
Mouse Mus musculus O09113 325 34140 S285 P A S L P G P S N V S G S P Q
Rat Rattus norvegicus A6YP92 566 58628 E513 R Q P T P A V E G A V A S G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9PVX0 317 34038 P273 G A M G P P P P Y Q C G A A F
Frog Xenopus laevis Q91574 335 37508 L294 N I F F T E S L L S G S A N G
Zebra Danio Brachydanio rerio Q6DGH9 315 34010 T276 P A S L S G P T N V T G S P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P56672 409 43154 S297 P P N M N S C S S V T P P P L
Honey Bee Apis mellifera XP_001120088 381 40473 G320 S G S G G G G G G V S C V A A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 79.3 N.A. 100 23.3 N.A. N.A. 34.1 29.5 82.1 N.A. 35.2 32.8 N.A. N.A.
Protein Similarity: 100 N.A. N.A. 80.3 N.A. 100 33 N.A. N.A. 47.3 44.4 87.3 N.A. 45.2 42.5 N.A. N.A.
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 13.3 N.A. N.A. 26.6 0 80 N.A. 26.6 26.6 N.A. N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 13.3 N.A. N.A. 33.3 6.6 93.3 N.A. 53.3 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 56 0 0 0 12 0 0 0 12 0 12 23 23 23 % A
% Cys: 0 0 0 0 0 0 12 0 0 0 12 12 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 12 0 12 0 0 0 0 0 0 0 % E
% Phe: 0 0 12 12 0 0 0 0 0 0 0 0 0 0 12 % F
% Gly: 12 12 0 23 12 56 12 12 23 0 12 56 0 12 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 45 0 0 0 12 12 0 0 0 0 0 12 % L
% Met: 0 0 12 12 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 12 0 12 0 0 0 45 0 0 0 0 12 0 % N
% Pro: 56 12 12 0 56 12 56 12 0 0 0 12 12 56 0 % P
% Gln: 0 12 0 0 0 0 0 0 0 12 0 0 0 0 45 % Q
% Arg: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 12 0 56 0 12 12 12 45 12 12 45 12 56 0 0 % S
% Thr: 0 0 0 12 12 0 0 12 0 0 23 0 0 0 0 % T
% Val: 0 0 0 0 0 0 12 0 0 67 12 0 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _