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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF123 All Species: 17.58
Human Site: S1001 Identified Species: 35.15
UniProt: Q5XPI4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5XPI4 NP_071347.2 1314 148515 S1001 L E D A N L P S L Q K P C P S
Chimpanzee Pan troglodytes XP_001164974 1317 148510 S1004 L E D A N L P S L Q K P C P S
Rhesus Macaque Macaca mulatta XP_001106313 1311 148222 S1001 L E D A N L P S L Q K P C P S
Dog Lupus familis XP_541883 1215 137377 A924 V A I N S Y S A L K N Y F G P
Cat Felis silvestris
Mouse Mus musculus Q5XPI3 1314 148633 S1001 P E D A N L P S L Q K P C P S
Rat Rattus norvegicus XP_002730009 1312 148274 S999 P E D A N L P S L Q K P C P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519085 463 53130 D172 L F Y N G K V D Y F D L Q R L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919007 690 77651 Q399 P C P S L L L Q R H M A E L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650425 1332 151027 L959 S L P L H Q G L C R S R S R N
Honey Bee Apis mellifera XP_393619 1163 132728 L872 R Y D R S P H L L K K G G S K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002310019 827 92644 L536 T F L Q N I L L K N R G A D C
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_850020 1280 144481 F985 S S F S S T V F Q A L L R D A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 98.7 80.8 N.A. 93.8 93.5 N.A. 26.9 N.A. N.A. 42.8 N.A. 30.2 35.8 N.A. N.A.
Protein Similarity: 100 97.3 99.2 83.5 N.A. 96.8 96.9 N.A. 31.5 N.A. N.A. 47.3 N.A. 50 54.4 N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 93.3 93.3 N.A. 6.6 N.A. N.A. 6.6 N.A. 0 20 N.A. N.A.
P-Site Similarity: 100 100 100 33.3 N.A. 93.3 93.3 N.A. 6.6 N.A. N.A. 13.3 N.A. 20 33.3 N.A. N.A.
Percent
Protein Identity: 21.3 N.A. N.A. 25.1 N.A. N.A.
Protein Similarity: 36 N.A. N.A. 42.6 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 42 0 0 0 9 0 9 0 9 9 0 9 % A
% Cys: 0 9 0 0 0 0 0 0 9 0 0 0 42 0 9 % C
% Asp: 0 0 50 0 0 0 0 9 0 0 9 0 0 17 0 % D
% Glu: 0 42 0 0 0 0 0 0 0 0 0 0 9 0 0 % E
% Phe: 0 17 9 0 0 0 0 9 0 9 0 0 9 0 0 % F
% Gly: 0 0 0 0 9 0 9 0 0 0 0 17 9 9 0 % G
% His: 0 0 0 0 9 0 9 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 9 0 0 9 17 50 0 0 0 9 % K
% Leu: 34 9 9 9 9 50 17 25 59 0 9 17 0 9 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 0 17 50 0 0 0 0 9 9 0 0 0 9 % N
% Pro: 25 0 17 0 0 9 42 0 0 0 0 42 0 42 9 % P
% Gln: 0 0 0 9 0 9 0 9 9 42 0 0 9 0 0 % Q
% Arg: 9 0 0 9 0 0 0 0 9 9 9 9 9 17 0 % R
% Ser: 17 9 0 17 25 0 9 42 0 0 9 0 9 9 42 % S
% Thr: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % T
% Val: 9 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 9 0 0 9 0 0 9 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _