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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF123
All Species:
19.39
Human Site:
S1173
Identified Species:
38.79
UniProt:
Q5XPI4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5XPI4
NP_071347.2
1314
148515
S1173
S
E
R
E
Q
A
T
S
V
L
L
A
D
P
C
Chimpanzee
Pan troglodytes
XP_001164974
1317
148510
S1176
S
E
R
E
Q
A
T
S
V
L
L
A
D
P
C
Rhesus Macaque
Macaca mulatta
XP_001106313
1311
148222
S1173
S
E
R
E
R
A
T
S
V
L
L
A
D
P
C
Dog
Lupus familis
XP_541883
1215
137377
S1080
V
A
P
S
F
L
N
S
V
L
N
Q
L
N
W
Cat
Felis silvestris
Mouse
Mus musculus
Q5XPI3
1314
148633
S1173
S
E
T
E
Q
A
T
S
V
L
L
A
D
P
C
Rat
Rattus norvegicus
XP_002730009
1312
148274
S1171
S
E
T
E
Q
A
T
S
V
L
L
A
D
P
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519085
463
53130
M328
E
I
L
D
G
I
V
M
I
Y
N
L
S
V
H
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919007
690
77651
V555
V
D
S
N
K
Q
G
V
S
R
A
A
S
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650425
1332
151027
V1147
S
D
L
R
P
Q
I
V
T
R
V
S
R
A
F
Honey Bee
Apis mellifera
XP_393619
1163
132728
E1028
L
L
E
I
P
D
L
E
S
V
D
H
F
P
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002310019
827
92644
S692
K
D
S
R
V
H
C
S
G
I
P
D
R
S
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850020
1280
144481
L1143
Q
Q
H
D
V
I
G
L
F
A
S
M
D
C
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
98.7
80.8
N.A.
93.8
93.5
N.A.
26.9
N.A.
N.A.
42.8
N.A.
30.2
35.8
N.A.
N.A.
Protein Similarity:
100
97.3
99.2
83.5
N.A.
96.8
96.9
N.A.
31.5
N.A.
N.A.
47.3
N.A.
50
54.4
N.A.
N.A.
P-Site Identity:
100
100
93.3
20
N.A.
93.3
93.3
N.A.
0
N.A.
N.A.
6.6
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
93.3
93.3
N.A.
13.3
N.A.
N.A.
20
N.A.
26.6
13.3
N.A.
N.A.
Percent
Protein Identity:
21.3
N.A.
N.A.
25.1
N.A.
N.A.
Protein Similarity:
36
N.A.
N.A.
42.6
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
42
0
0
0
9
9
50
0
9
9
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
42
% C
% Asp:
0
25
0
17
0
9
0
0
0
0
9
9
50
0
0
% D
% Glu:
9
42
9
42
0
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
9
0
0
0
9
0
9
% F
% Gly:
0
0
0
0
9
0
17
0
9
0
0
0
0
0
0
% G
% His:
0
0
9
0
0
9
0
0
0
0
0
9
0
0
9
% H
% Ile:
0
9
0
9
0
17
9
0
9
9
0
0
0
0
9
% I
% Lys:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
9
17
0
0
9
9
9
0
50
42
9
9
0
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
9
0
0
9
0
0
0
17
0
0
9
0
% N
% Pro:
0
0
9
0
17
0
0
0
0
0
9
0
0
50
9
% P
% Gln:
9
9
0
0
34
17
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
25
17
9
0
0
0
0
17
0
0
17
0
0
% R
% Ser:
50
0
17
9
0
0
0
59
17
0
9
9
17
9
0
% S
% Thr:
0
0
17
0
0
0
42
0
9
0
0
0
0
0
0
% T
% Val:
17
0
0
0
17
0
9
17
50
9
9
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _