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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF123
All Species:
15.76
Human Site:
S723
Identified Species:
31.52
UniProt:
Q5XPI4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5XPI4
NP_071347.2
1314
148515
S723
T
R
E
D
I
E
G
S
H
W
N
E
G
L
L
Chimpanzee
Pan troglodytes
XP_001164974
1317
148510
N720
T
L
D
P
S
L
P
N
S
P
V
E
G
S
H
Rhesus Macaque
Macaca mulatta
XP_001106313
1311
148222
S723
T
R
E
D
I
E
G
S
H
W
N
E
G
L
L
Dog
Lupus familis
XP_541883
1215
137377
S666
S
N
P
R
A
S
F
S
E
E
A
Y
I
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q5XPI3
1314
148633
S723
T
R
E
D
I
E
G
S
H
W
N
E
G
L
L
Rat
Rattus norvegicus
XP_002730009
1312
148274
S721
T
R
E
D
I
E
G
S
H
W
N
E
G
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519085
463
53130
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919007
690
77651
G141
S
L
L
E
I
L
D
G
V
V
M
I
Y
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650425
1332
151027
L688
M
E
A
S
L
C
E
L
L
D
L
C
I
I
F
Honey Bee
Apis mellifera
XP_393619
1163
132728
P614
S
I
I
L
D
T
A
P
L
P
V
N
I
V
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002310019
827
92644
P278
Y
P
I
Q
G
F
L
P
L
K
A
P
P
S
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850020
1280
144481
S712
I
D
D
K
P
S
T
S
N
Q
S
D
P
D
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
98.7
80.8
N.A.
93.8
93.5
N.A.
26.9
N.A.
N.A.
42.8
N.A.
30.2
35.8
N.A.
N.A.
Protein Similarity:
100
97.3
99.2
83.5
N.A.
96.8
96.9
N.A.
31.5
N.A.
N.A.
47.3
N.A.
50
54.4
N.A.
N.A.
P-Site Identity:
100
20
100
6.6
N.A.
100
100
N.A.
0
N.A.
N.A.
13.3
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
33.3
100
13.3
N.A.
100
100
N.A.
0
N.A.
N.A.
26.6
N.A.
13.3
13.3
N.A.
N.A.
Percent
Protein Identity:
21.3
N.A.
N.A.
25.1
N.A.
N.A.
Protein Similarity:
36
N.A.
N.A.
42.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
9
0
0
0
17
0
0
0
9
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
9
17
34
9
0
9
0
0
9
0
9
0
9
9
% D
% Glu:
0
9
34
9
0
34
9
0
9
9
0
42
0
0
0
% E
% Phe:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
17
% F
% Gly:
0
0
0
0
9
0
34
9
0
0
0
0
42
0
0
% G
% His:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
9
% H
% Ile:
9
9
17
0
42
0
0
0
0
0
0
9
25
9
0
% I
% Lys:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
0
17
9
9
9
17
9
9
25
0
9
0
0
34
42
% L
% Met:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
9
9
0
34
9
0
9
0
% N
% Pro:
0
9
9
9
9
0
9
17
0
17
0
9
17
9
9
% P
% Gln:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
34
0
9
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
25
0
0
9
9
17
0
50
9
0
9
0
0
17
0
% S
% Thr:
42
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
9
17
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _