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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF123
All Species:
18.18
Human Site:
Y1218
Identified Species:
36.36
UniProt:
Q5XPI4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5XPI4
NP_071347.2
1314
148515
Y1218
S
L
Q
S
Y
A
D
Y
I
S
A
D
E
L
A
Chimpanzee
Pan troglodytes
XP_001164974
1317
148510
Y1221
S
L
Q
S
Y
V
D
Y
I
S
A
D
E
L
A
Rhesus Macaque
Macaca mulatta
XP_001106313
1311
148222
Y1218
S
L
Q
S
Y
A
D
Y
I
S
A
D
E
L
A
Dog
Lupus familis
XP_541883
1215
137377
L1125
V
C
A
T
C
F
D
L
S
V
S
L
L
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q5XPI3
1314
148633
Y1218
S
L
Q
S
Y
T
D
Y
I
S
A
E
E
L
A
Rat
Rattus norvegicus
XP_002730009
1312
148274
Y1216
S
L
Q
S
Y
A
D
Y
I
S
A
E
E
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519085
463
53130
Y373
P
D
T
R
K
D
I
Y
E
E
L
M
K
S
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919007
690
77651
D600
F
S
L
H
T
Y
T
D
Y
I
S
T
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650425
1332
151027
R1192
G
N
F
D
P
S
S
R
P
H
I
D
P
L
T
Honey Bee
Apis mellifera
XP_393619
1163
132728
P1073
T
Q
T
L
L
I
E
P
S
F
Q
M
S
T
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002310019
827
92644
R737
Y
C
P
V
R
D
I
R
I
V
H
R
E
S
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850020
1280
144481
H1188
Q
L
E
N
F
L
S
H
L
I
N
R
A
S
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
98.7
80.8
N.A.
93.8
93.5
N.A.
26.9
N.A.
N.A.
42.8
N.A.
30.2
35.8
N.A.
N.A.
Protein Similarity:
100
97.3
99.2
83.5
N.A.
96.8
96.9
N.A.
31.5
N.A.
N.A.
47.3
N.A.
50
54.4
N.A.
N.A.
P-Site Identity:
100
93.3
100
6.6
N.A.
86.6
93.3
N.A.
6.6
N.A.
N.A.
6.6
N.A.
13.3
0
N.A.
N.A.
P-Site Similarity:
100
93.3
100
20
N.A.
93.3
100
N.A.
13.3
N.A.
N.A.
13.3
N.A.
20
13.3
N.A.
N.A.
Percent
Protein Identity:
21.3
N.A.
N.A.
25.1
N.A.
N.A.
Protein Similarity:
36
N.A.
N.A.
42.6
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
25
0
0
0
0
42
0
9
0
42
% A
% Cys:
0
17
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
0
17
50
9
0
0
0
34
0
0
9
% D
% Glu:
0
0
9
0
0
0
9
0
9
9
0
17
59
9
9
% E
% Phe:
9
0
9
0
9
9
0
0
0
9
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
9
0
0
0
9
0
9
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
17
0
50
17
9
0
0
0
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
0
50
9
9
9
9
0
9
9
0
9
9
9
50
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% M
% Asn:
0
9
0
9
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
9
0
9
0
9
0
0
9
9
0
0
0
9
0
0
% P
% Gln:
9
9
42
0
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
9
9
0
0
17
0
0
0
17
0
9
9
% R
% Ser:
42
9
0
42
0
9
17
0
17
42
17
0
9
25
9
% S
% Thr:
9
0
17
9
9
9
9
0
0
0
0
9
0
9
9
% T
% Val:
9
0
0
9
0
9
0
0
0
17
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
42
9
0
50
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _