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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF123 All Species: 18.79
Human Site: Y404 Identified Species: 37.58
UniProt: Q5XPI4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5XPI4 NP_071347.2 1314 148515 Y404 D L G L Q I H Y L R L T I A I
Chimpanzee Pan troglodytes XP_001164974 1317 148510 Y401 D L G L Q I H Y L R L T I A I
Rhesus Macaque Macaca mulatta XP_001106313 1311 148222 Y404 D L G L Q I H Y L R L T I A I
Dog Lupus familis XP_541883 1215 137377 A392 F L R G V M E A G T P V Q A Q
Cat Felis silvestris
Mouse Mus musculus Q5XPI3 1314 148633 Y404 D L G L Q I H Y L R L T M S I
Rat Rattus norvegicus XP_002730009 1312 148274 Y402 D L G L Q I H Y L R L T M A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519085 463 53130
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919007 690 77651
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650425 1332 151027 A406 D Y E K H R Q A L G M L H C L
Honey Bee Apis mellifera XP_393619 1163 132728 T340 T C L D L L W T F L E E H E I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002310019 827 92644
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_850020 1280 144481 G415 L T E C P Y S G P Y P Y L A L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 98.7 80.8 N.A. 93.8 93.5 N.A. 26.9 N.A. N.A. 42.8 N.A. 30.2 35.8 N.A. N.A.
Protein Similarity: 100 97.3 99.2 83.5 N.A. 96.8 96.9 N.A. 31.5 N.A. N.A. 47.3 N.A. 50 54.4 N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 86.6 86.6 N.A. 0 N.A. N.A. 0 N.A. 13.3 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 100 100 N.A. 0 N.A. N.A. 0 N.A. 26.6 13.3 N.A. N.A.
Percent
Protein Identity: 21.3 N.A. N.A. 25.1 N.A. N.A.
Protein Similarity: 36 N.A. N.A. 42.6 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 0 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 17 0 0 0 0 0 50 0 % A
% Cys: 0 9 0 9 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 50 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 17 0 0 0 9 0 0 0 9 9 0 9 0 % E
% Phe: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 0 0 42 9 0 0 0 9 9 9 0 0 0 0 0 % G
% His: 0 0 0 0 9 0 42 0 0 0 0 0 17 0 0 % H
% Ile: 0 0 0 0 0 42 0 0 0 0 0 0 25 0 42 % I
% Lys: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 50 9 42 9 9 0 0 50 9 42 9 9 0 17 % L
% Met: 0 0 0 0 0 9 0 0 0 0 9 0 17 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 9 0 0 0 9 0 17 0 0 0 0 % P
% Gln: 0 0 0 0 42 0 9 0 0 0 0 0 9 0 9 % Q
% Arg: 0 0 9 0 0 9 0 0 0 42 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 0 % S
% Thr: 9 9 0 0 0 0 0 9 0 9 0 42 0 0 0 % T
% Val: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 9 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 9 0 42 0 9 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _