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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF123 All Species: 19.39
Human Site: Y880 Identified Species: 38.79
UniProt: Q5XPI4 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5XPI4 NP_071347.2 1314 148515 Y880 S Y S A L K N Y F G P V H S M
Chimpanzee Pan troglodytes XP_001164974 1317 148510 Y883 S Y S A L K N Y F G P V H S M
Rhesus Macaque Macaca mulatta XP_001106313 1311 148222 Y880 S Y S A L K N Y F G P V H S M
Dog Lupus familis XP_541883 1215 137377 L814 S H W N E G L L L G R P P E E
Cat Felis silvestris
Mouse Mus musculus Q5XPI3 1314 148633 Y880 S Y S A L K N Y F G P V H S M
Rat Rattus norvegicus XP_002730009 1312 148274 Y878 S Y S A L K N Y F G P V H S M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519085 463 53130 R62 L R R R A Y E R G C Q R L K K
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919007 690 77651 A289 D T L I Q L A A I L A K H F A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650425 1332 151027 F837 L L D A V M D F S H H D L K A
Honey Bee Apis mellifera XP_393619 1163 132728 N762 D L C V G L R N H M H P T A H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002310019 827 92644 A426 S G S Y S Y L A M V C H I L Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_850020 1280 144481 S874 C F H V L R K S D P P F V P S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 98.7 80.8 N.A. 93.8 93.5 N.A. 26.9 N.A. N.A. 42.8 N.A. 30.2 35.8 N.A. N.A.
Protein Similarity: 100 97.3 99.2 83.5 N.A. 96.8 96.9 N.A. 31.5 N.A. N.A. 47.3 N.A. 50 54.4 N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 100 100 N.A. 0 N.A. N.A. 6.6 N.A. 6.6 0 N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 100 100 N.A. 0 N.A. N.A. 6.6 N.A. 26.6 6.6 N.A. N.A.
Percent
Protein Identity: 21.3 N.A. N.A. 25.1 N.A. N.A.
Protein Similarity: 36 N.A. N.A. 42.6 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 50 9 0 9 17 0 0 9 0 0 9 17 % A
% Cys: 9 0 9 0 0 0 0 0 0 9 9 0 0 0 0 % C
% Asp: 17 0 9 0 0 0 9 0 9 0 0 9 0 0 0 % D
% Glu: 0 0 0 0 9 0 9 0 0 0 0 0 0 9 9 % E
% Phe: 0 9 0 0 0 0 0 9 42 0 0 9 0 9 0 % F
% Gly: 0 9 0 0 9 9 0 0 9 50 0 0 0 0 0 % G
% His: 0 9 9 0 0 0 0 0 9 9 17 9 50 0 9 % H
% Ile: 0 0 0 9 0 0 0 0 9 0 0 0 9 0 0 % I
% Lys: 0 0 0 0 0 42 9 0 0 0 0 9 0 17 9 % K
% Leu: 17 17 9 0 50 17 17 9 9 9 0 0 17 9 0 % L
% Met: 0 0 0 0 0 9 0 0 9 9 0 0 0 0 42 % M
% Asn: 0 0 0 9 0 0 42 9 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 9 50 17 9 9 0 % P
% Gln: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 9 % Q
% Arg: 0 9 9 9 0 9 9 9 0 0 9 9 0 0 0 % R
% Ser: 59 0 50 0 9 0 0 9 9 0 0 0 0 42 9 % S
% Thr: 0 9 0 0 0 0 0 0 0 0 0 0 9 0 0 % T
% Val: 0 0 0 17 9 0 0 0 0 9 0 42 9 0 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 42 0 9 0 17 0 42 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _