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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW10
All Species:
10.61
Human Site:
S774
Identified Species:
25.93
UniProt:
Q5XX13
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5XX13
NP_113644.3
1052
119760
S774
Q
S
Q
G
K
S
K
S
P
R
R
D
A
D
D
Chimpanzee
Pan troglodytes
XP_001146277
676
76116
A409
D
A
D
D
V
E
K
A
Q
K
Q
G
Q
L
E
Rhesus Macaque
Macaca mulatta
XP_001084872
1050
119876
S774
Q
S
Q
G
K
S
K
S
P
R
R
D
A
D
D
Dog
Lupus familis
XP_536650
1059
121515
S777
Q
S
Q
G
K
L
K
S
P
R
R
D
G
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUS0
1030
117673
V756
Q
E
F
S
K
S
R
V
H
L
K
Q
T
K
N
Rat
Rattus norvegicus
XP_001077639
1016
115893
R745
K
Q
E
F
S
K
S
R
V
L
L
K
Q
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510270
1115
125614
A844
R
F
P
A
V
E
A
A
E
A
I
L
R
R
G
Chicken
Gallus gallus
XP_415592
693
76558
L426
S
Q
M
R
R
L
T
L
K
T
R
A
L
C
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692449
852
95928
S585
A
Q
V
A
Q
R
E
S
T
R
A
A
M
W
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794564
1304
145734
S855
H
N
V
Q
G
L
R
S
G
N
I
D
A
Q
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
94.1
77.4
N.A.
69.3
68.3
N.A.
41.9
29
N.A.
26.3
N.A.
N.A.
N.A.
N.A.
26
Protein Similarity:
100
61
96.5
87.1
N.A.
80.9
80.5
N.A.
59.3
43.1
N.A.
44.8
N.A.
N.A.
N.A.
N.A.
45.6
P-Site Identity:
100
6.6
100
73.3
N.A.
20
0
N.A.
0
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
40
100
73.3
N.A.
40
13.3
N.A.
13.3
20
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
20
0
0
10
20
0
10
10
20
30
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
10
0
10
10
0
0
0
0
0
0
0
40
0
20
20
% D
% Glu:
0
10
10
0
0
20
10
0
10
0
0
0
0
0
10
% E
% Phe:
0
10
10
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
30
10
0
0
0
10
0
0
10
10
0
10
% G
% His:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% I
% Lys:
10
0
0
0
40
10
40
0
10
10
10
10
0
20
10
% K
% Leu:
0
0
0
0
0
30
0
10
0
20
10
10
10
10
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
20
% N
% Pro:
0
0
10
0
0
0
0
0
30
0
0
0
0
0
0
% P
% Gln:
40
30
30
10
10
0
0
0
10
0
10
10
20
10
0
% Q
% Arg:
10
0
0
10
10
10
20
10
0
40
40
0
10
10
10
% R
% Ser:
10
30
0
10
10
30
10
50
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
10
0
10
10
0
0
10
10
10
% T
% Val:
0
0
20
0
20
0
0
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _