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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW10
All Species:
8.18
Human Site:
T735
Identified Species:
20
UniProt:
Q5XX13
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5XX13
NP_113644.3
1052
119760
T735
E
S
V
S
S
K
Q
T
V
I
Q
E
L
L
P
Chimpanzee
Pan troglodytes
XP_001146277
676
76116
P370
E
L
L
P
G
K
P
P
K
S
R
V
L
L
K
Rhesus Macaque
Macaca mulatta
XP_001084872
1050
119876
T735
E
S
V
S
S
K
Q
T
V
I
Q
E
L
L
P
Dog
Lupus familis
XP_536650
1059
121515
T738
D
S
M
S
S
K
Q
T
V
A
Q
E
S
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUS0
1030
117673
D717
N
K
V
K
K
S
K
D
K
E
E
E
R
E
E
Rat
Rattus norvegicus
XP_001077639
1016
115893
K706
K
N
K
T
K
K
N
K
D
K
E
E
E
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510270
1115
125614
K805
V
S
E
E
I
Q
V
K
A
K
Y
F
P
R
K
Chicken
Gallus gallus
XP_415592
693
76558
G387
V
M
W
D
Y
M
L
G
A
E
R
D
M
V
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692449
852
95928
P546
H
V
S
P
K
N
V
P
R
S
T
E
R
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794564
1304
145734
R816
T
N
L
T
H
S
T
R
F
L
S
N
R
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
94.1
77.4
N.A.
69.3
68.3
N.A.
41.9
29
N.A.
26.3
N.A.
N.A.
N.A.
N.A.
26
Protein Similarity:
100
61
96.5
87.1
N.A.
80.9
80.5
N.A.
59.3
43.1
N.A.
44.8
N.A.
N.A.
N.A.
N.A.
45.6
P-Site Identity:
100
26.6
100
66.6
N.A.
13.3
13.3
N.A.
6.6
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
40
100
80
N.A.
26.6
40
N.A.
13.3
26.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
20
10
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
0
10
10
0
0
10
0
0
0
% D
% Glu:
30
0
10
10
0
0
0
0
0
20
20
60
10
10
20
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
20
0
0
0
0
0
% I
% Lys:
10
10
10
10
30
50
10
20
20
20
0
0
0
0
20
% K
% Leu:
0
10
20
0
0
0
10
0
0
10
0
0
30
40
20
% L
% Met:
0
10
10
0
0
10
0
0
0
0
0
0
10
0
0
% M
% Asn:
10
20
0
0
0
10
10
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
20
0
0
10
20
0
0
0
0
10
0
20
% P
% Gln:
0
0
0
0
0
10
30
0
0
0
30
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
10
0
20
0
30
20
0
% R
% Ser:
0
40
10
30
30
20
0
0
0
20
10
0
10
10
0
% S
% Thr:
10
0
0
20
0
0
10
30
0
0
10
0
0
0
10
% T
% Val:
20
10
30
0
0
0
20
0
30
0
0
10
0
10
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _