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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANO1
All Species:
18.48
Human Site:
S466
Identified Species:
45.19
UniProt:
Q5XXA6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5XXA6
NP_060513.5
986
114078
S466
E
A
R
V
L
E
K
S
L
K
K
E
S
R
N
Chimpanzee
Pan troglodytes
XP_001159940
976
111572
M458
E
T
K
V
R
E
K
M
L
K
E
S
N
K
E
Rhesus Macaque
Macaca mulatta
XP_001118212
1094
124416
K549
K
V
R
E
K
M
L
K
E
S
N
K
K
K
E
Dog
Lupus familis
XP_854489
1037
118791
S525
E
A
R
V
L
E
K
S
L
R
K
E
S
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHY3
960
110898
S466
E
A
R
V
L
E
K
S
L
R
K
E
S
R
N
Rat
Rattus norvegicus
Q6IFT6
860
97152
I402
D
C
S
D
Y
E
D
I
E
E
R
P
R
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507078
891
103110
M433
E
H
W
K
R
K
Q
M
R
L
N
Y
R
W
D
Chicken
Gallus gallus
XP_421072
955
110458
S463
E
A
K
V
L
E
K
S
L
R
K
E
H
K
H
Frog
Xenopus laevis
NP_001128709
979
113207
S461
E
A
K
V
L
Q
K
S
L
K
K
E
Y
R
S
Zebra Danio
Brachydanio rerio
Q4V8U5
646
74505
Y187
K
R
L
S
F
S
W
Y
K
K
I
K
L
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
51.4
86.4
N.A.
89.7
36.5
N.A.
78.5
83.9
77.5
22.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
74.6
64.8
90
N.A.
93.1
53.8
N.A.
83.8
90.1
88.1
37.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
40
6.6
80
N.A.
93.3
6.6
N.A.
6.6
66.6
73.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
26.6
100
N.A.
100
26.6
N.A.
26.6
93.3
93.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
10
0
0
0
0
0
0
0
10
% D
% Glu:
70
0
0
10
0
60
0
0
20
10
10
50
0
0
20
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
10
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% I
% Lys:
20
0
30
10
10
10
60
10
10
40
50
20
10
40
0
% K
% Leu:
0
0
10
0
50
0
10
0
60
10
0
0
10
0
0
% L
% Met:
0
0
0
0
0
10
0
20
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
20
0
10
0
20
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% P
% Gln:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
10
% Q
% Arg:
0
10
40
0
20
0
0
0
10
30
10
0
20
30
0
% R
% Ser:
0
0
10
10
0
10
0
50
0
10
0
10
30
10
20
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
60
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
10
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
10
0
0
10
0
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _