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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANO1 All Species: 4.24
Human Site: S90 Identified Species: 10.37
UniProt: Q5XXA6 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5XXA6 NP_060513.5 986 114078 S90 V Q H S D T P S G A R S V K Q
Chimpanzee Pan troglodytes XP_001159940 976 111572 K94 V S N G E T G K E P H A G D P
Rhesus Macaque Macaca mulatta XP_001118212 1094 124416 S182 G H S L A I V S N G E T G K E
Dog Lupus familis XP_854489 1037 118791 P149 V Q H S D A A P A A R G A R Q
Cat Felis silvestris
Mouse Mus musculus Q8BHY3 960 110898 L90 G L Q N D M V L G T R S V R Q
Rat Rattus norvegicus Q6IFT6 860 97152 S45 G K Q Q V A P S R V G S S A N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507078 891 103110 S76 Y Q Y K R S S S S K T L A R R
Chicken Gallus gallus XP_421072 955 110458 A90 A Q H N D A G A R G A K Q D P
Frog Xenopus laevis NP_001128709 979 113207 H96 H S P K D D H H L P G G G G D
Zebra Danio Brachydanio rerio Q4V8U5 646 74505
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.7 51.4 86.4 N.A. 89.7 36.5 N.A. 78.5 83.9 77.5 22.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 74.6 64.8 90 N.A. 93.1 53.8 N.A. 83.8 90.1 88.1 37.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 13.3 53.3 N.A. 40 20 N.A. 13.3 20 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 33.3 26.6 60 N.A. 53.3 26.6 N.A. 40 33.3 6.6 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 10 30 10 10 10 20 10 10 20 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 50 10 0 0 0 0 0 0 0 20 10 % D
% Glu: 0 0 0 0 10 0 0 0 10 0 10 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 30 0 0 10 0 0 20 0 20 20 20 20 30 10 0 % G
% His: 10 10 30 0 0 0 10 10 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 20 0 0 0 10 0 10 0 10 0 20 0 % K
% Leu: 0 10 0 10 0 0 0 10 10 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 20 0 0 0 0 10 0 0 0 0 0 10 % N
% Pro: 0 0 10 0 0 0 20 10 0 20 0 0 0 0 20 % P
% Gln: 0 40 20 10 0 0 0 0 0 0 0 0 10 0 30 % Q
% Arg: 0 0 0 0 10 0 0 0 20 0 30 0 0 30 10 % R
% Ser: 0 20 10 20 0 10 10 40 10 0 0 30 10 0 0 % S
% Thr: 0 0 0 0 0 20 0 0 0 10 10 10 0 0 0 % T
% Val: 30 0 0 0 10 0 20 0 0 10 0 0 20 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _