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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CD276 All Species: 13.33
Human Site: S523 Identified Species: 36.67
UniProt: Q5ZPR3 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5ZPR3 NP_001019907.1 534 57235 S523 A L Q P L K H S D S K E D D G
Chimpanzee Pan troglodytes XP_523213 534 57296 S523 A L Q P L K C S D S K E D D G
Rhesus Macaque Macaca mulatta XP_001094177 534 57283 S523 A L Q P L K H S D S K E D D G
Dog Lupus familis XP_854204 686 73568 S675 A L R P L K H S E S K E D D G
Cat Felis silvestris
Mouse Mus musculus Q8VE98 316 33983 N307 R P L K P S E N K E D D G Q E
Rat Rattus norvegicus Q7TPB4 316 34056 N307 R P L K H S E N K E D D G Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507561 212 22768 A203 I A S S A I S A V P L L Q L I
Chicken Gallus gallus
Frog Xenopus laevis Q68EV1 308 34001 G299 P L K V T S P G E D D D A E C
Zebra Danio Brachydanio rerio NP_001074091 300 32705 A291 E A R V L E E A K S E A T T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 97.1 73.9 N.A. 54.6 55 N.A. 25 N.A. 32 31.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99 98.5 75.6 N.A. 57.4 57.6 N.A. 31 N.A. 44.1 43.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 100 86.6 N.A. 0 0 N.A. 0 N.A. 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 13.3 13.3 N.A. 6.6 N.A. 33.3 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 45 23 0 0 12 0 0 23 0 0 0 12 12 0 0 % A
% Cys: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 12 % C
% Asp: 0 0 0 0 0 0 0 0 34 12 34 34 45 45 0 % D
% Glu: 12 0 0 0 0 12 34 0 23 23 12 45 0 12 23 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 12 0 0 0 0 23 0 45 % G
% His: 0 0 0 0 12 0 34 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 0 0 0 12 0 0 0 0 0 0 0 0 12 % I
% Lys: 0 0 12 23 0 45 0 0 34 0 45 0 0 0 0 % K
% Leu: 0 56 23 0 56 0 0 0 0 0 12 12 0 12 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 23 0 0 0 0 0 0 0 % N
% Pro: 12 23 0 45 12 0 12 0 0 12 0 0 0 0 0 % P
% Gln: 0 0 34 0 0 0 0 0 0 0 0 0 12 23 0 % Q
% Arg: 23 0 23 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 12 12 0 34 12 45 0 56 0 0 0 0 0 % S
% Thr: 0 0 0 0 12 0 0 0 0 0 0 0 12 12 0 % T
% Val: 0 0 0 23 0 0 0 0 12 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _