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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCXD3
All Species:
21.21
Human Site:
S241
Identified Species:
51.85
UniProt:
Q63HM9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q63HM9
NP_001005473.1
321
36313
S241
T
E
R
R
K
K
G
S
F
F
I
S
Q
V
V
Chimpanzee
Pan troglodytes
XP_001146704
329
37141
S247
S
E
R
A
S
R
G
S
F
H
V
S
Q
A
I
Rhesus Macaque
Macaca mulatta
XP_001087469
321
36262
S241
T
E
R
R
K
K
G
S
F
F
I
S
Q
V
V
Dog
Lupus familis
XP_855317
321
36189
S241
T
E
R
R
K
K
G
S
F
F
I
S
Q
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLJ3
321
36295
S241
T
E
R
R
K
K
G
S
F
F
I
S
Q
V
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505659
240
27310
L161
W
E
K
D
Y
Q
V
L
V
F
Y
H
S
P
V
Chicken
Gallus gallus
XP_416631
315
36185
V235
S
R
Y
G
T
F
H
V
S
Q
A
I
L
T
P
Frog
Xenopus laevis
NP_001079447
307
35506
R228
L
E
K
T
L
T
E
R
S
K
H
G
T
F
H
Zebra Danio
Brachydanio rerio
Q58EK3
322
36584
T241
K
D
R
R
R
K
G
T
F
F
V
S
Q
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786994
320
36076
R241
I
L
N
A
H
H
T
R
G
R
P
P
D
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.2
99.3
98.4
N.A.
98.1
N.A.
N.A.
73.5
50.1
49.8
81.3
N.A.
N.A.
N.A.
N.A.
38.3
Protein Similarity:
100
72.3
100
99
N.A.
99.6
N.A.
N.A.
74.1
69.7
68.2
92.5
N.A.
N.A.
N.A.
N.A.
59.8
P-Site Identity:
100
46.6
100
100
N.A.
100
N.A.
N.A.
20
0
6.6
66.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
73.3
100
100
N.A.
100
N.A.
N.A.
33.3
6.6
13.3
93.3
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
0
0
0
0
0
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
70
0
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
60
60
0
0
0
10
10
% F
% Gly:
0
0
0
10
0
0
60
0
10
0
0
10
0
0
0
% G
% His:
0
0
0
0
10
10
10
0
0
10
10
10
0
0
10
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
40
10
0
0
10
% I
% Lys:
10
0
20
0
40
50
0
0
0
10
0
0
0
10
0
% K
% Leu:
10
10
0
0
10
0
0
10
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
10
% P
% Gln:
0
0
0
0
0
10
0
0
0
10
0
0
60
0
0
% Q
% Arg:
0
10
60
50
10
10
0
20
0
10
0
0
0
0
0
% R
% Ser:
20
0
0
0
10
0
0
50
20
0
0
60
10
0
0
% S
% Thr:
40
0
0
10
10
10
10
10
0
0
0
0
10
10
0
% T
% Val:
0
0
0
0
0
0
10
10
10
0
20
0
0
50
60
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
10
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _