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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF213
All Species:
21.21
Human Site:
Y666
Identified Species:
77.78
UniProt:
Q63HN8
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q63HN8
NP_065965.3
3280
373981
Y666
S
D
V
A
E
K
L
Y
I
Q
Q
I
V
Q
R
Chimpanzee
Pan troglodytes
XP_511726
4149
473678
Y1572
S
D
V
A
E
K
L
Y
I
Q
Q
I
V
Q
R
Rhesus Macaque
Macaca mulatta
XP_001110315
4229
480306
Y1688
S
D
A
A
E
K
L
Y
I
Q
Q
I
V
Q
R
Dog
Lupus familis
XP_540474
3388
386230
Y781
N
N
N
A
E
K
L
Y
I
Q
Q
I
M
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
XP_001081768
5230
593496
Y2644
N
D
S
A
E
R
L
Y
I
Q
Q
I
V
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420083
4031
460684
G781
Y
E
L
S
Q
E
S
G
F
N
D
F
M
L
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921030
4291
493201
Y1722
N
D
H
T
E
K
M
Y
I
K
Q
I
V
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.9
66.2
70
N.A.
N.A.
46.2
N.A.
N.A.
22.9
N.A.
41.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
76.3
70.2
80.7
N.A.
N.A.
52.9
N.A.
N.A.
39.2
N.A.
55.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
N.A.
80
N.A.
N.A.
0
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
N.A.
93.3
N.A.
N.A.
40
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
72
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% C
% Asp:
0
72
0
0
0
0
0
0
0
0
15
0
0
0
0
% D
% Glu:
0
15
0
0
86
15
0
0
0
0
0
0
0
15
0
% E
% Phe:
0
0
0
0
0
0
0
0
15
0
0
15
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% G
% His:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
86
0
0
86
0
0
0
% I
% Lys:
0
0
0
0
0
72
0
0
0
15
0
0
0
0
0
% K
% Leu:
0
0
15
0
0
0
72
0
0
0
0
0
0
15
0
% L
% Met:
0
0
0
0
0
0
15
0
0
0
0
0
29
0
0
% M
% Asn:
43
15
15
0
0
0
0
0
0
15
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
15
0
0
0
0
72
86
0
0
72
0
% Q
% Arg:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
86
% R
% Ser:
43
0
15
15
0
0
15
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
29
0
0
0
0
0
0
0
0
0
72
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
0
0
0
0
86
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _