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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EGFLAM All Species: 30.91
Human Site: S439 Identified Species: 61.82
UniProt: Q63HQ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q63HQ2 NP_689616.2 1017 111271 S439 H G R G D F M S L A I I R R S
Chimpanzee Pan troglodytes XP_517796 1010 110654 S440 H G R G D F M S L A I I R R S
Rhesus Macaque Macaca mulatta XP_001083161 1017 111150 S439 H G R G D F M S L A I I R R S
Dog Lupus familis XP_853970 1017 112185 S439 Y G R G D F M S L A I I R R S
Cat Felis silvestris
Mouse Mus musculus Q4VBE4 1017 110717 S439 H G R G D F M S L A L I R R S
Rat Rattus norvegicus B4F785 1005 109652 S435 H G R G D F M S L A L I R R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509895 380 41684
Chicken Gallus gallus XP_425019 1062 116282 S492 H G R G D F M S L A I I R R S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001339765 1244 135834 S479 H G R G D F T S L A L I R G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611082 1361 150280 A453 D L T G D F M A L L L N K G F
Honey Bee Apis mellifera XP_393275 929 101638 G382 R V E G R S K G L F A R I T F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787979 862 94451 A314 F D C G Q G A A V I T S R T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.3 97.7 88 N.A. 88.4 87.5 N.A. 30.5 71.1 N.A. 48 N.A. 20.7 31.1 N.A. 30.9
Protein Similarity: 100 96.9 99 93.2 N.A. 93.2 91.6 N.A. 34.1 81.4 N.A. 62.6 N.A. 36.3 48.2 N.A. 47.9
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 0 100 N.A. 73.3 N.A. 33.3 13.3 N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 0 100 N.A. 80 N.A. 53.3 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 17 0 67 9 0 0 0 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 0 0 75 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 9 0 0 0 0 75 0 0 0 9 0 0 0 0 17 % F
% Gly: 0 67 0 92 0 9 0 9 0 0 0 0 0 17 0 % G
% His: 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 42 67 9 0 0 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 0 0 9 0 9 % K
% Leu: 0 9 0 0 0 0 0 0 84 9 34 0 0 0 0 % L
% Met: 0 0 0 0 0 0 67 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 67 0 9 0 0 0 0 0 0 9 75 59 0 % R
% Ser: 0 0 0 0 0 9 0 67 0 0 0 9 0 0 67 % S
% Thr: 0 0 9 0 0 0 9 0 0 0 9 0 0 17 0 % T
% Val: 0 9 0 0 0 0 0 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _