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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EGFLAM All Species: 16.97
Human Site: Y806 Identified Species: 33.94
UniProt: Q63HQ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q63HQ2 NP_689616.2 1017 111271 Y806 C R P R K E G Y D C D C P L G
Chimpanzee Pan troglodytes XP_517796 1010 110654 K804 G G S C R P R K E G Y D C D C
Rhesus Macaque Macaca mulatta XP_001083161 1017 111150 Y806 C R P R K E G Y D C D C P L G
Dog Lupus familis XP_853970 1017 112185 Y806 C R P R K E G Y E C D C P L G
Cat Felis silvestris
Mouse Mus musculus Q4VBE4 1017 110717 Y806 C R P R K E G Y E C D C P L G
Rat Rattus norvegicus B4F785 1005 109652 K799 G G S C R P R K E G Y E C D C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509895 380 41684 G177 P L G K A L S G A D V G E C S
Chicken Gallus gallus XP_425019 1062 116282 K856 G G S C V P K K D S Y E C D C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001339765 1244 135834 W843 G G T C R A K W D E Y D C D C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611082 1361 150280 Y815 C V P Q M E S Y E C R C S I H
Honey Bee Apis mellifera XP_393275 929 101638 I726 P A P D D N T I L D S S P S K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787979 862 94451 Y659 E C H P L Q E Y Y F C D C R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.3 97.7 88 N.A. 88.4 87.5 N.A. 30.5 71.1 N.A. 48 N.A. 20.7 31.1 N.A. 30.9
Protein Similarity: 100 96.9 99 93.2 N.A. 93.2 91.6 N.A. 34.1 81.4 N.A. 62.6 N.A. 36.3 48.2 N.A. 47.9
P-Site Identity: 100 0 100 93.3 N.A. 93.3 0 N.A. 0 6.6 N.A. 6.6 N.A. 40 13.3 N.A. 6.6
P-Site Similarity: 100 13.3 100 100 N.A. 100 13.3 N.A. 6.6 6.6 N.A. 20 N.A. 60 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 9 0 0 9 0 0 0 0 0 0 % A
% Cys: 42 9 0 34 0 0 0 0 0 42 9 42 42 9 34 % C
% Asp: 0 0 0 9 9 0 0 0 34 17 34 25 0 34 0 % D
% Glu: 9 0 0 0 0 42 9 0 42 9 0 17 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 34 34 9 0 0 0 34 9 0 17 0 9 0 0 34 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 0 % I
% Lys: 0 0 0 9 34 0 17 25 0 0 0 0 0 0 9 % K
% Leu: 0 9 0 0 9 9 0 0 9 0 0 0 0 34 9 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 17 0 50 9 0 25 0 0 0 0 0 0 42 0 0 % P
% Gln: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 34 0 34 25 0 17 0 0 0 9 0 0 9 0 % R
% Ser: 0 0 25 0 0 0 17 0 0 9 9 9 9 9 9 % S
% Thr: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % T
% Val: 0 9 0 0 9 0 0 0 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 9 0 34 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _