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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A10
All Species:
3.64
Human Site:
T104
Identified Species:
8.89
UniProt:
Q63ZE4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q63ZE4
NP_001034841.3
531
59034
T104
Q
L
L
H
L
N
G
T
I
H
S
T
S
E
A
Chimpanzee
Pan troglodytes
XP_508511
476
53526
T58
V
H
M
V
D
N
N
T
G
S
G
N
E
T
G
Rhesus Macaque
Macaca mulatta
XP_001084980
550
60036
T101
Q
L
L
D
P
N
A
T
A
T
S
W
S
E
A
Dog
Lupus familis
XP_533256
552
61738
F105
L
L
H
V
N
G
T
F
T
N
M
T
E
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFZ5
553
60176
A105
L
T
E
S
N
A
T
A
T
N
W
S
D
A
A
Rat
Rattus norvegicus
Q3ZAV1
553
60226
A105
L
I
E
S
N
T
T
A
T
N
W
S
D
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507099
556
61556
G105
L
L
T
E
N
G
T
G
P
Q
P
H
E
P
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66J54
558
62434
W99
I
A
G
T
N
R
T
W
A
N
S
S
Q
L
A
Zebra Danio
Brachydanio rerio
Q6NYN7
560
61953
D102
N
T
S
E
S
L
W
D
E
S
M
A
E
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95R48
567
63148
G90
Y
T
E
E
Y
L
N
G
S
I
P
R
S
S
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87
48.7
65
N.A.
44.8
45.2
N.A.
46
N.A.
38.7
37.3
N.A.
28.5
N.A.
N.A.
N.A.
Protein Similarity:
100
87.7
62.9
78.6
N.A.
61.2
61.4
N.A.
61.5
N.A.
60.9
59.4
N.A.
48.3
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
60
13.3
N.A.
6.6
0
N.A.
13.3
N.A.
13.3
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
60
20
N.A.
20
20
N.A.
13.3
N.A.
26.6
0
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
10
20
20
0
0
10
0
20
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
10
0
0
10
0
0
0
0
20
0
20
% D
% Glu:
0
0
30
30
0
0
0
0
10
0
0
0
40
20
10
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
20
10
20
10
0
10
0
0
0
10
% G
% His:
0
10
10
10
0
0
0
0
0
10
0
10
0
0
0
% H
% Ile:
10
10
0
0
0
0
0
0
10
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
40
40
20
0
10
20
0
0
0
0
0
0
0
10
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
20
0
0
0
0
% M
% Asn:
10
0
0
0
50
30
20
0
0
40
0
10
0
0
10
% N
% Pro:
0
0
0
0
10
0
0
0
10
0
20
0
0
20
0
% P
% Gln:
20
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
10
20
10
0
0
0
10
20
30
30
30
10
0
% S
% Thr:
0
30
10
10
0
10
50
30
30
10
0
20
0
20
0
% T
% Val:
10
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
10
0
0
20
10
0
0
0
% W
% Tyr:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _